SCHEMBL2807538

SCHEMBL2807538

Cc1c(C(=O)O)sc(N)c1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CISD2 Q8N5K1 3/20 0.51
MAPT P10636 4/20 0.50
RAB9A P51151 2/20 0.50
NPC1 O15118 1/20 0.50
ALDH1A1 P00352 10/20 0.49
HPGD P15428 4/20 0.49
LMNA P02545 2/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
HSD17B10 Q99714 2/20 0.47
ALOX15 P16050 1/20 0.47
MAPK1 P28482 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
KDM4E B2RXH2 1/20 0.46
ADORA1 P30542 1/20 0.45
GAA P10253 2/20 0.44
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3066973 0.88 ALDH1A1 (0.62) CISD2MAPTRAB9ANPC1ALDH1A1
SCHEMBL27475039 0.82 ALDH1A1 (0.47) CISD2MAPTRAB9ANPC1ALDH1A1
SCHEMBL3497284 0.80 ALDH1A1 (0.61) CISD2MAPTRAB9ANPC1ALDH1A1
SCHEMBL27663685 0.80 ALDH1A1 (0.71) CISD2MAPTRAB9ANPC1ALDH1A1
SCHEMBL11039338 0.79 CISD2 (0.37) CISD2MAPTRAB9ANPC1ALDH1A1
SCHEMBL8054398 0.79 GRM6 (0.59) CISD2MAPTRAB9ANPC1ALDH1A1
SCHEMBL3496735 0.79 ALDH1A1 (0.53) CISD2MAPTRAB9ANPC1ALDH1A1
SCHEMBL18357869 0.77 GPR35 (0.47) MAPTALDH1A1HPGDLMNAMEN1
SCHEMBL25195925 0.77 GPR35 (0.53) MAPTRAB9ANPC1ALDH1A1HPGD
SCHEMBL28773543 0.77 ALDH1A1 (0.41) CISD2MAPTRAB9ANPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108164381-B Process for the manufacture of nitriles and their corresponding amines 中国石化扬子石油化工有限公司 2022-02-11 CN claimed
CN-108546223-B Process for the manufacture of nitriles and their corresponding amines 中国石化扬子石油化工有限公司 2022-02-11 CN claimed
CN-105016940-A Process for the manufacture of nitriles and their corresponding amines SINOPEC YANGZI PETROCHEMICAL 2015-11-04 CN claimed
CN-105016939-A Preparation methods of nitrile and corresponding amine SINOPEC YANGZI PETROCHEMICAL 2015-11-04 CN claimed
CN-105001032-A Process for the manufacture of nitriles and their corresponding amines SINOPEC YANGZI PETROCHEMICAL 2015-10-28 CN claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
CN-119968081-A Perovskite precursor solution, perovskite film, and preparation methods and applications thereof 德沪涂膜设备(苏州)有限公司 2025-05-09 CN disclosed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
JP-2022035834-A 2,4-DIOXO-1,4-DIHYDROTHIENOPYRIMIDINE COMPOUND AND BACTERICIDE FOR AGRICULTURAL AND HORTICULTURAL USE 日本曹達株式会社 2022-03-04 JP disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 WO disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
CN-101557826-A Therapeutic agent for urinary tract disease ASKA PHARM CO LTD (JP) 2009-10-14 CN disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed
EP-1370562-A1 THIENO[2,3-D]PYRIMIDINDIONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS Warner-Lambert Company LLC (US) 2003-12-17 EP disclosed
WO-2002064598-A1 THIENO'2,3-D PYRIMIDINDIONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS WARNER-LAMBERT COMPANY LLC (US) 2002-08-22 WO disclosed
US-4257942-A New water-insoluble azo dyes AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) 1981-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 CISD2 2111/4885MAPT 2575/4885RAB9A 4090/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB CISD2 2841/4885MAPT 2140/4885RAB9A 4503/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA CISD2 1582/4885MAPT 3115/4885RAB9A 4824/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA CISD2 665/4885MAPT 3104/4885RAB9A 4315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.