Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 4/20 | 0.42 |
| ▸ | VCP | P55072 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28339042 | 1.00 | FBP1 (0.42) | FBP1VCPKMT2AMEN1GLA | |
| SCHEMBL4655499 | 0.79 | TTR (0.49) | KMT2AMEN1GLAHTTMAPT | |
| SCHEMBL7126316 | 0.79 | GPR35 (0.47) | KMT2AMEN1ERN1ALDH1A1TGM2 | |
| SCHEMBL27361987 | 0.76 | ERN1 (0.47) | KMT2AMEN1HTTERN1MAPT | |
| SCHEMBL28376956 | 0.75 | ALDH1A1 (0.49) | KMT2AGLAHTTMAPTALDH1A1 | |
| SCHEMBL20162383 | 0.75 | ALDH1A1 (0.46) | KMT2AMEN1GLAHTTMAPT | |
| SCHEMBL28338592 | 0.73 | FBP1 (0.46) | FBP1VCPKMT2AMEN1MAPT | |
| SCHEMBL28338591 | 0.73 | FBP1 (0.46) | FBP1VCPKMT2AMEN1MAPT | |
| SCHEMBL28199720 | 0.72 | LMNA (0.53) | KMT2AMEN1HTTMAPTALDH1A1 | |
| SCHEMBL226894 | 0.72 | GAA (0.57) | KMT2AMEN1MAPTALDH1A1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452205-A | A kind of preparation method for constructing 3- methene base -3,4- dihydrocoumarin framework compound | UNIV TIANJIN AGRICULTURAL | 2019-11-15 | — | — | CN | disclosed |