SCHEMBL283594

SCHEMBL283594

Cc1ccc(CC(=O)O)cc1F

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.50
HPGD P15428 4/20 0.50
HSD17B10 Q99714 4/20 0.50
MAPT P10636 3/20 0.50
GAA P10253 3/20 0.50
TSHR P16473 3/20 0.50
NFKB1 P19838 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
RGS12 O14924 1/20 0.50
LMNA P02545 1/20 0.50
POLB P06746 1/20 0.50
APEX1 P27695 1/20 0.50
THPO P40225 1/20 0.50
BLM P54132 1/20 0.50
GNAI1 P63096 1/20 0.50
PMP22 Q01453 1/20 0.50
HIF1A Q16665 1/20 0.50
SLC22A12 Q96S37 1/20 0.49
KMT2A Q03164 2/20 0.49
ALDH1A1 P00352 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1699671 0.85 KDM4E (0.50) KDM4EHPGDHSD17B10MAPTGAA
SCHEMBL10864263 0.85 HDAC1 (0.44) MAPTLMNAPOLBKMT2AALDH1A1
SCHEMBL6977259 0.83 HDAC1 (0.43) MAPTLMNAKMT2AALDH1A1MEN1
SCHEMBL4108950 0.83 KMT2A (0.44) MAPTLMNAPOLBKMT2AALDH1A1
SCHEMBL5956162 0.83 CA2 (0.47) KDM4ELMNAPOLBKMT2AALDH1A1
SCHEMBL154429 0.82 KDM4E (0.55) KDM4EHPGDHSD17B10MAPTGAA
SCHEMBL969589 0.82 HPGD (0.55) KDM4EHPGDHSD17B10MAPTGAA
SCHEMBL585740 0.81 FFAR1 (0.55) KMT2AFFAR4RXRG
SCHEMBL13592400 0.81 DAO (0.40) LMNAKMT2AALDH1A1PTGS1AKR1C3
SCHEMBL18912182 0.80 PARP1 (0.43) TDP1POLBAPEX1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250376621-A1 HALIDE PEROVSKITE NANOCRYSTAL PARTICLES, EMITTERS, MANUFACTURING METHOD THEREOF SEOUL NAT UNIV R&DB FOUNDATION (KR) 2025-12-11 US disclosed
US-20250376385-A1 PEROVSKITE POWDER, LIGHT EMITTING LAYER FOR LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING THE SAME SEOUL NAT UNIV R&DB FOUNDATION (KR) 2025-12-11 US disclosed
US-12351577-B2 Inhibiting cyclic AMP-responsive element-binding protein (CREB) FORMA THERAPEUTICS, INC. (US) 2025-07-08 US disclosed
US-20250188079-A1 INHIBITING CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN (CREB) FORMA THERAPEUTICS, INC. 2025-06-12 US disclosed
US-20240309038-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2024-09-19 US disclosed
US-20240215280-A1 IN SITU CORE/SHELL PEROVSKITE NANOCRYSTAL MATERIAL, METHOD OF PREPARATION THEREOF, AND LIGHT EMITTING DEVICE COMPRISING THE SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2024-06-27 US disclosed
US-20240158692-A1 IN-SITU CORE/SHELL NANOPARTICLE STRUCTURED METAL HALIDE PEROVSKITE LUMINESCENT MATERIAL, LIGHT EMITTING DEVICE INCLUDING THE SAME, AND MANUFACTURING METHOD THEREOF SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2024-05-16 US disclosed
CN-117043156-A Novel galectin inhibitors of galectins 格莱克特生物技术公司 2023-11-10 CN disclosed
US-20230348779-A1 FLUORESCENT COMPOUND AND FLUORESCENTLY LABELED BIOLOGICAL SUBSTANCE USING THE SAME FUJIFILM CORPORATION (JP) 2023-11-02 US disclosed
EP-4267568-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS Galecto Biotech AB (DK) 2023-11-01 EP disclosed
US-20070099960-A1 LXR receptor modulators LABORATOIRES FOURNIER S.A. (FR) 2007-05-03 US disclosed
US-20070099960-A1 LXR receptor modulators LABORATOIRES FOURNIER S.A. (FR) 2007-05-03 US disclosed
WO-2007027527-A2 ISOINDOLE-IMIDE COMPOUNDS AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME CELGENE CORPORATION (US) 2007-03-08 WO disclosed
US-20070049618-A1 Isoindole-imide compounds and compositions comprising and methods of using the same CELGENE CORPORATION 2007-03-01 US disclosed
WO-2007000550-A2 NOVEL INDOLINE COMPOUNDS LABORATOIRES FOURNIER S.A. (FR) 2007-01-04 WO disclosed
WO-2006056752-A1 PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES ASTRAZENECA AB (SE) 2006-06-01 WO disclosed
EP-1619180-A1 CaSR ANTAGONIST JAPAN TOBACCO INC. (JP) 2006-01-25 EP disclosed
US-20050171195-A1 P2X7 antagonists for treating neuropathic pain ABBOTT LABORATORIES 2005-08-04 US disclosed
US-20050032796-A1 Compounds as for example, 2'-[1-[(2R)-3-[[1-(3-fluoro-4-methylphenyl)-2-methylpropan-2-yl]amino]-2-hydroxypropoxy]ethyl]-3-methylbiphenyl-4-carboxylic acid, having a calcium-sensing receptor antagonistic action; therapeutic drug for osteoporosis JAPAN TOBACCO INC. 2005-02-10 US disclosed
US-6645973-B1 Heterocyclic amines such as 1-carboxymethyl-4-(4-chlorophenyl) spiro(2H-1-benzopyran-2,4'-piperidine)hydrochloride used for therapy of nervous system disorders; Alzheimer's, Parkinson's and Huntington's disease AKZO NOBEL (NL) 2003-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050171195-A1 P2X7 antagonists for treating neuropathic pain P2RX3, P2RX7, P2RX1 KDM4E 3084/4885HPGD 1153/4885HSD17B10 4378/4885
US-20070099960-A1 LXR receptor modulators NR1H2, NR1H3, PPARD KDM4E 3026/4885HPGD 1240/4885HSD17B10 407/4885
US-20250188079-A1 INHIBITING CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN (CREB) CREBBP, CREB1, EP300 KDM4E 1457/4885HPGD 1408/4885HSD17B10 3062/4885
US-20240309038-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS LGALS3, LGALS1, LGALS3BP KDM4E 4324/4885HPGD 2794/4885HSD17B10 3389/4885
US-20050032796-A1 Compounds as for example, 2'-[1-[(2R)-3-[[1-(3-fluoro-4-methylphenyl)-2-methylpropan-2-yl]amino]-2-hydroxypropoxy]ethyl]-3-methylbiphenyl-4-carboxylic acid, having a calcium-sensing receptor antagonistic action; therapeutic drug for osteoporosis CASR, CALCR, GRK2 KDM4E 1893/4885HPGD 2078/4885HSD17B10 2364/4885
US-20070049618-A1 Isoindole-imide compounds and compositions comprising and methods of using the same SI, CYP3A5, CYP2D6 KDM4E 1501/4885HPGD 331/4885HSD17B10 1214/4885
US-12351577-B2 Inhibiting cyclic AMP-responsive element-binding protein (CREB) CREBBP, CREB1, EP300 KDM4E 1457/4885HPGD 1408/4885HSD17B10 3062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.