SCHEMBL28368261

SCHEMBL28368261

Cc1cc(N)c(S(=O)(=O)[O-])cc1Cl.[Na+]

nearest known ligand 0.52

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 known ✓ O43570 8/20 0.40
CA1 known ✓ P00915 8/20 0.40
CA2 known ✓ P00918 8/20 0.40
CA4 known ✓ P22748 2/20 0.40
P2RY4 known ✓ P51582 2/20 0.40
CD44 P16070 1/20 0.52
CA9 Q16790 8/20 0.40
CA6 P23280 2/20 0.40
CA5A P35218 2/20 0.40
CA7 P43166 2/20 0.40
CA14 Q9ULX7 2/20 0.40
CA5B Q9Y2D0 2/20 0.40
CA3 P07451 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TSHR P16473 2/20 0.39
GLA P06280 1/20 0.39
LMNA P02545 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9706813 0.93 CD44 (0.52) CD44CA12CA1CA2CA9
Potassium Ion SCHEMBL28541293 0.89 CD44 (0.52) CD44CA12CA1CA2CA9
SCHEMBL1806789 0.81 CA1 (0.62) CD44CA12CA1CA2CA9
SCHEMBL10400529 0.80 CA1 (0.50) CD44CA12CA1CA2CA9
SCHEMBL315975 0.79 CD44 (0.54) CD44CA12CA1CA2CA9
SCHEMBL29350461 0.79 CD44 (0.54) CD44CA12CA1CA2CA9
SCHEMBL9350744 0.79 CA12 (0.38) CA12CA1CA2CA9CA4
SCHEMBL9349924 0.78 PKLR (0.45) CA12CA1CA2CA9ALDH1A1
SCHEMBL27990790 0.78 CD44 (0.52) CD44CA12CA1CA2CA9
SCHEMBL375199 0.76 CD44 (0.50) CD44CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110769931-A Catalyst for generating free radical, method for producing oxidation reaction product, chemical, and chemical for agricultural and livestock use 株式会社ACENET 2020-02-07 CN disclosed