SCHEMBL2837145

SCHEMBL2837145

c1ccc(N(c2ccccn2)c2ccc3ccc4c(N(c5ccccc5)c5ccccn5)ccc5ccc2c3c54)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35
ALDH1A1 P00352 6/20 0.35
USP2 O75604 1/20 0.34
SMN1; SMN2 Q16637 4/20 0.34
TDP1 Q9NUW8 3/20 0.34
OPRK1 P41145 3/20 0.34
KDM4E B2RXH2 3/20 0.34
LMNA P02545 3/20 0.34
MAPT P10636 2/20 0.34
HTT P42858 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
NPC1 O15118 1/20 0.34
POLB P06746 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HPGD P15428 1/20 0.34
ALOX12 P18054 1/20 0.34
HDAC6 Q9UBN7 2/20 0.34
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13320960 1.00 MAOA (0.35) MAOAMAOBALDH1A1USP2SMN1; SMN2
SCHEMBL16144421 0.98 MAOA (0.34) MAOAMAOBALDH1A1USP2SMN1; SMN2
SCHEMBL21093138 0.91 MAOA (0.33) MAOAMAOBALDH1A1SMN1; SMN2TDP1
SCHEMBL13304298 0.90 KDM4E (0.37) MAOAMAOBALDH1A1SMN1; SMN2TDP1
SCHEMBL16144469 0.89 NOS1 (0.30)
SCHEMBL16144398 0.89 LMNA (0.34) MAOAMAOBALDH1A1SMN1; SMN2TDP1
SCHEMBL17342358 0.89 ALDH1A1 (0.33) MAOAMAOBALDH1A1USP2SMN1; SMN2
SCHEMBL25028135 0.88 ALDH1A1 (0.34) MAOAMAOBALDH1A1USP2SMN1; SMN2
SCHEMBL16144387 0.88
SCHEMBL16144494 0.88 HDAC6 (0.34) MAOAMAOBALDH1A1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230403926-A1 ORGANIC LIGHT-EMITTING DEVICE WITH IMPROVED LIFESPAN CHARACTERISTICS UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2023-12-14 US disclosed
US-20230403926-A1 ORGANIC LIGHT-EMITTING DEVICE WITH IMPROVED LIFESPAN CHARACTERISTICS UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2023-12-14 US disclosed
EP-1437395-B2 Organic electroluminescent device LG DISPLAY CO LTD (KR) 2015-08-26 EP disclosed
US-8436344-B2 Organic electroluminescent device LG DISPLAY CO., LTD. (KR) 2013-05-07 US disclosed
US-8436344-B2 Organic electroluminescent device LG DISPLAY CO., LTD. (KR) 2013-05-07 US disclosed
US-8436344-B2 Organic electroluminescent device LG DISPLAY CO., LTD. (KR) 2013-05-07 US disclosed
EP-1437395-B1 Organic electroluminescent device LG DISPLAY CO LTD (KR) 2011-12-14 EP disclosed
US-20100155714-A1 ORGANIC ELECTROLUMINESCENT DEVICE LG DISPLAY CO., LTD. (KR) 2010-06-24 US disclosed
US-20100155714-A1 ORGANIC ELECTROLUMINESCENT DEVICE LG DISPLAY CO., LTD. (KR) 2010-06-24 US disclosed
US-20100155714-A1 ORGANIC ELECTROLUMINESCENT DEVICE LG DISPLAY CO., LTD. (KR) 2010-06-24 US disclosed
US-20100109517-A1 PYRENE POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-05-06 US disclosed
US-7700201-B2 Organic electroluminescent device LG DISPLAY CO., LTD. (KR) 2010-04-20 US disclosed
US-7700201-B2 Organic electroluminescent device LG DISPLAY CO., LTD. (KR) 2010-04-20 US disclosed
US-7700201-B2 Organic electroluminescent device LG DISPLAY CO., LTD. (KR) 2010-04-20 US disclosed
US-20040137270-A1 Organic electroluminescent device LG ELECTRONICS INC. 2004-07-15 US disclosed
EP-1437395-A2 Organic electroluminescent device LG ELECTRONICS INC. (KR) 2004-07-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100155714-A1 ORGANIC ELECTROLUMINESCENT DEVICE L1CAM, AOC2, AOC1 MAOA 32/4885MAOB 113/4885ALDH1A1 5/4885
US-20100109517-A1 PYRENE POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME TERB1, AHR, CYP1A1 MAOA 2225/4885MAOB 2264/4885ALDH1A1 1933/4885
US-20230403926-A1 ORGANIC LIGHT-EMITTING DEVICE WITH IMPROVED LIFESPAN CHARACTERISTICS ELP1, ELOVL1, L3MBTL1 MAOA 3214/4885MAOB 3854/4885ALDH1A1 438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.