Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Adenine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 known ✓ | P11362 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 4/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL1035727 | 1.00 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL338435 | 1.00 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL2411187 | 0.98 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL8509836 | 0.98 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL4908366 | 0.96 | PI4KA (0.38) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL9275554 | 0.93 | PI4KA (0.38) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL385841 | 0.88 | PI4KA (0.45) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL8110 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL3414603 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL3416954 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12484819-B2 | Syringe apparatus and methods | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2025-12-02 | — | — | US | claimed |
| EP-4627345-A1 | MEASUREMENT OF REACTIVE OXYGEN SPECIES TO ASSESS RED BLOOD CELL QUALITY | University Of Maryland, Baltimore (US) | 2025-10-08 | — | — | EP | claimed |
| US-20250298040-A1 | MEASUREMENT OF REACTIVE OXYGEN SPECIES TO ASSESS RED BLOOD CELL QUALITY | UNIVERSITY OF MARYLAND, BALTIMORE | 2025-09-25 | — | — | US | claimed |
| CN-119930723-A | Method for extracting adenine phosphate in Cordyceps militaris | 博斯创想(上海)医疗科技有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-116093351-B | Composite nano catalyst loaded on nitrogen-doped carbon and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2025-05-06 | — | — | CN | claimed |
| CN-118419869-A | Bi (I) containing bismuth, phosphorus and nitrogen material, preparation method and application | 德清县浙工大莫干山研究院 | 2024-08-02 | — | — | CN | claimed |
| WO-2024119059-A1 | MEASUREMENT OF REACTIVE OXYGEN SPECIES TO ASSESS RED BLOOD CELL QUALITY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2024-06-06 | — | — | WO | claimed |
| CN-118121612-A | Pharmaceutical composition of antitumor drug and adenine phosphate, eutectic and preparation method and application thereof | 江苏海洋大学 | 2024-06-04 | — | — | CN | claimed |
| CN-118084914-A | Synthesis method of medicinal adenine phosphate | 天津力生制药股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-116144720-B | Method for producing pseudouridine by enzyme method | 苏州华赛生物工程技术有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-102677072-A | Formula of green corrosion inhibition cleaning agent for hot-dip coated steel and application thereof | UNIV CHINA PETROLEUM | 2012-09-19 | — | — | CN | claimed |
| CN-101921468-A | Polylactic acid composition containing sulfoacid compound and phosphorus-containing organic compound and preparation method thereof | TORAY FIBER RES INST CN CO LTD | 2010-12-22 | — | — | CN | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| CN-101444499-A | Compound and new usage of composition thereof | SHANGHAI AMBROSIA PHARMACEUTIC (CN) | 2009-06-03 | — | — | CN | claimed |
| CN-101416960-A | Use of coumarether and composition thereof | SHANGHAI AMBROSIA PHARMACEUTIC (CN) | 2009-04-29 | — | — | CN | claimed |
| CN-101245308-A | Vinegar rich in vitamin B and producing method thereof | ZHENJIANG DANHE VINEGAR INDUST (CN) | 2008-08-20 | — | — | CN | claimed |
| CN-1275100-C | Photoresist stripping liquid composition and stripping methof for photoresist using photoresist stripping liquid composition | DONGWOO FINE CHEM CO LTD (KR) | 2006-09-13 | — | — | CN | claimed |
| WO-2005042060-A2 | METHOD AND COMPOSITION COMPRISING PYRUVATE, INOSINE, ADENINE, PHOSPHATE AND AN AZIRIDINO COMPOUND FOR TREATING A BIOLOGICAL SAMPLE | V.I. TECHNOLOGIES, INC. (US) | 2005-05-12 | — | — | WO | claimed |
| US-20050074743-A1 | Method and composition for treating a biological sample | V.I. TECHNOLOGIES, INC. | 2005-04-07 | — | — | US | claimed |
| CN-1577110-A | Photoresist stripping liquid composition and stripping methof for photoresist using photoresist stripping liquid composition | DONGWOO FINE CHEM CO LTD (KR) | 2005-02-09 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050074743-A1 | Method and composition for treating a biological sample | APOB, MB, ALPP | FGFR1 4436/4885PI4KA 4576/4885PI4K2B 4369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.