Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SHMT1 | P34896 | 10/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | EIF4E | P06730 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2836889 | 0.82 | GABRA1 (0.37) | KDM4EALDH1A1HPGDGAA | |
| SCHEMBL5732815 | 0.82 | CNR1 (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6205890 | 0.82 | EIF4E (0.30) | EIF4E | |
| SCHEMBL2836314 | 0.82 | MAOA (0.41) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL2835936 | 0.81 | GAA (0.46) | ALDH1A1GAALMNA | |
| SCHEMBL2836064 | 0.80 | MAPT (0.43) | KDM4ESMN1; SMN2LMNAEIF4E | |
| SCHEMBL2841129 | 0.78 | KDM4E (0.35) | KDM4EALDH1A1GAA | |
| SCHEMBL2835555 | 0.77 | MAPT (0.33) | MDM2 | |
| SCHEMBL1573450 | 0.76 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL2836047 | 0.75 | ALDH1A1 (0.39) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754880-B2 | Uracils having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2010-07-13 | — | — | US | claimed |
| US-20060025591-A1 | New uracils having a herbicidal activity | ISEM S.R.L. (IT) | 2006-02-02 | — | — | US | claimed |
| US-7754880-B2 | Uracils having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2010-07-13 | — | — | US | disclosed |
| US-20060025591-A1 | New uracils having a herbicidal activity | ISEM S.R.L. (IT) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025591-A1 | New uracils having a herbicidal activity | UNG, DDT, UMPS | KDM4E 1747/4885ALDH1A1 53/4885HPGD 2001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.