Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28598096 | 0.86 | ALDH1A1 (0.40) | KMT2AALDH1A1KDM4ETHRBMEN1 | |
| SCHEMBL10842060 | 0.73 | KMT2A (0.67) | KMT2AALDH1A1KDM4ETHRBMEN1 | |
| SCHEMBL21246906 | 0.73 | L3MBTL1 (0.59) | KMT2AKDM4EMEN1L3MBTL1 | |
| SCHEMBL28824689 | 0.73 | KMT2A (0.50) | KMT2AALDH1A1KDM4ETHRBMEN1 | |
| SCHEMBL1333179 | 0.71 | HTT (0.54) | KMT2AALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL28120658 | 0.70 | KMT2A (0.41) | KMT2AALDH1A1KDM4ETHRBMEN1 | |
| SCHEMBL27617492 | 0.70 | PKM (0.48) | KMT2AALDH1A1KDM4ETHRBMEN1 | |
| SCHEMBL6123415 | 0.69 | KDM4E (0.41) | KMT2AALDH1A1KDM4ETHRBMEN1 | |
| SCHEMBL28512335 | 0.68 | KDM4E (0.39) | KMT2AALDH1A1KDM4ETHRBMEN1 | |
| SCHEMBL18530830 | 0.65 | ELANE (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727385-B | Preparation method of polysubstituted dihydropyrimido indolone derivative | 青岛科技大学 | 2020-09-08 | — | — | CN | disclosed |