Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL6361862 | 0.88 | — | — | |
| Acrylic Acid SCHEMBL9105086 | 0.83 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL9109011 | 0.83 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL9943789 | 0.83 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL5318157 | 0.83 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL10820891 | 0.83 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL9105167 | 0.83 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL10624495 | 0.83 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL5315356 | 0.83 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL5315576 | 0.83 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368549-A | Refining system and refining method of low-odor polyether polyol and polyether polyol obtained by refining method | 中国石油化工股份有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-109201107-B | FCC gasoline mercaptan etherification catalyst and preparation method thereof | 淮北德昇科技有限公司 | 2021-12-07 | — | — | CN | disclosed |
| CN-109439365-B | C4Process for hydrogenating unsaturated hydrocarbons | 谷育英 | 2021-04-20 | — | — | CN | disclosed |
| CN-109433220-B | Nickel-based saturated hydrogenation catalyst and preparation method thereof | 谷育英 | 2021-04-16 | — | — | CN | disclosed |
| CN-109679685-B | C5Distillate saturation hydrogenation method | 谷育英 | 2021-04-16 | — | — | CN | disclosed |
| CN-109439364-B | Unsaturated C5Distillate hydrogenation process | 谷育英 | 2021-04-16 | — | — | CN | disclosed |
| CN-109679677-B | Mercaptan etherification method for FCC light gasoline fraction | 博兴兴业精细化工产业发展有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-109468143-B | Method for removing diolefin from catalytically cracked gasoline | 滨州市沾化区蓝乔生物科技有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-109468142-B | Catalyst for removing alkadiene from distillate oil and preparation method thereof | 山东省安正安全咨询服务有限公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-109207189-B | Mercaptan etherification method for FCC gasoline | 博兴兴业精细化工产业发展有限公司 | 2020-12-15 | — | — | CN | disclosed |
| CN-109468144-B | Method for removing diolefin from FCC gasoline light fraction | 博兴兴业精细化工产业发展有限公司 | 2020-12-15 | — | — | CN | disclosed |
| CN-109468141-B | C4Process for the saturation hydrogenation of distillates | 博兴兴业精细化工产业发展有限公司 | 2020-12-15 | — | — | CN | disclosed |
| CN-109207188-B | Catalytic cracking light gasoline mercaptan etherification method | 高秀铃 | 2020-11-17 | — | — | CN | disclosed |
| CN-109370639-B | Mercaptan etherification method for FCC gasoline | 高秀铃 | 2020-11-17 | — | — | CN | disclosed |
| CN-109468140-B | Catalyst for saturated hydrogenation of hydrocarbons and preparation method thereof | 宁夏鹏旭环保科技有限公司 | 2020-11-13 | — | — | CN | disclosed |