Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44289 | 0.87 | MAPT (0.33) | KDM4ELMNAHSD17B10HPGDMAPT | |
| SCHEMBL14690221 | 0.84 | MAPT (0.32) | KDM4ELMNAMAPT | |
| Ethylene Glycol SCHEMBL4451270 | 0.81 | MAPT (0.31) | LMNAMAPT | |
| SCHEMBL7707716 | 0.81 | SLC22A6 (0.44) | KDM4ELMNATP53L3MBTL1HSD17B10 | |
| SCHEMBL8844752 | 0.81 | MAPT (0.33) | KDM4ELMNAMAPTTDP1 | |
| SCHEMBL30442196 | 0.80 | ACHE (0.39) | KDM4ELMNATP53L3MBTL1ALDH1A1 | |
| SCHEMBL18145367 | 0.80 | ELANE (0.37) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL44290 | 0.79 | LMNA (0.35) | KDM4ELMNAL3MBTL1CA12CA1 | |
| SCHEMBL5526503 | 0.79 | ELANE (0.32) | — | |
| SCHEMBL9706733 | 0.79 | ADRA1A (0.52) | KDM4ELMNATP53L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210130546-A1 | METHODS FOR PREPARING POLYMERIC REAGENTS AND COMPOSITIONS OF POLYMERIC REAGENTS | NEKTAR THERAPEUTICS (US) | 2021-05-06 | — | — | US | disclosed |
| US-10421838-B2 | Methods for preparing polymeric reagents and compositions of polymeric reagents | NEKTAR THERAPEUTICS (US) | 2019-09-24 | — | — | US | disclosed |
| US-20170283552-A1 | METHODS FOR PREPARING POLYMERIC REAGENTS AND COMPOSITIONS OF POLYMERIC REAGENTS | NEKTAR THERAPEUTICS | 2017-10-05 | — | — | US | disclosed |
| US-9732189-B2 | Methods for preparing polymeric reagents and compositions of polymeric reagents | NEKTAR THERAPEUTICS (US) | 2017-08-15 | — | — | US | disclosed |
| US-20160289382-A1 | METHODS FOR PREPARING POLYMERIC REAGENTS AND COMPOSITIONS OF POLYMERIC REAGENTS | NEKTAR THERAPEUTICS | 2016-10-06 | — | — | US | disclosed |
| US-9334364-B2 | Methods for preparing polymeric reagents and compositions of polymeric reagents | NEKTAR THERAPEUTICS (US) | 2016-05-10 | — | — | US | disclosed |
| EP-1922350-B1 | METHODS FOR PREPARING POLYMERIC REAGENTS | NEKTAR THERAPEUTICS (US) | 2015-01-07 | — | — | EP | disclosed |
| US-20140323742-A1 | METHODS FOR PREPARING POLYMERIC REAGENTS AND COMPOSITIONS OF POLYMERIC REAGENTS | NEKTAR THERAPEUTICS | 2014-10-30 | — | — | US | disclosed |
| US-8809489-B2 | Methods for preparing polymeric reagents and compositions of polymeric reagents | NEKTAR THERAPEUTICS (US) | 2014-08-19 | — | — | US | disclosed |
| US-20130253203-A1 | Methods for Preparing Polymeric Reagents and Compositions of Polymeric Reagents | NEKTAR THERAPEUTICS (US) | 2013-09-26 | — | — | US | disclosed |
| US-8461295-B2 | Methods for preparing polymeric reagents and compositions of polymeric reagents | NEKTAR THERAPEUTICS (US) | 2013-06-11 | — | — | US | disclosed |
| US-20120214952-A1 | Methods for Preparing Polymeric Reagents and Compositions of Polymeric Reagents | NEKTAR THERAPEUTICS (US) | 2012-08-23 | — | — | US | disclosed |
| US-8193306-B2 | Methods for preparing polymeric reagents and compositions of polymeric reagents | NEKTAR THERAPEUTICS (US) | 2012-06-05 | — | — | US | disclosed |
| US-20100256310-A1 | Methods for Preparing Polymeric Reagents and Compositions of Polymeric Reagents | NEKTAR THERAPEUTICS (US) | 2010-10-07 | — | — | US | disclosed |
| US-7767784-B2 | Active carbonate esters of water-soluble polyoxyethylene glycol | NEKTAR THERAPEUTICS (US) | 2010-08-03 | — | — | US | disclosed |
| EP-1922350-A2 | METHODS FOR PREPARING POLYMERIC REAGENTS AND COMPOSITIONS OF POLYMERIC REAGENTS | Nektar Therapeutics AL, Corporation (US) | 2008-05-21 | — | — | EP | disclosed |
| US-20080064851-A1 | Active carbonate esters of water-soluble polyoxyethylene glycol | NEKTAR THERAPEUTICS | 2008-03-13 | — | — | US | disclosed |
| WO-2007016560-A9 | METHODS FOR PREPARING CARBONATE ESTERS OF POLY(ETYLENE GLYCOL) | NEKTAR THERAPEUTICS AL CORP (US) | 2007-05-31 | — | — | WO | disclosed |
| WO-2007016560-A2 | METHODS FOR PREPARING CARBONATE ESTERS OF POLY(ETYLENE GLYCOL) | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130546-A1 | METHODS FOR PREPARING POLYMERIC REAGENTS AND COMPOSITIONS OF POLYMERIC REAGENTS | SI, PHYKPL, PHOSPHO1 | KDM4E 1654/4885LMNA 745/4885TP53 1613/4885 |
| US-10421838-B2 | Methods for preparing polymeric reagents and compositions of polymeric reagents | SI, PHYKPL, PHOSPHO1 | KDM4E 1654/4885LMNA 745/4885TP53 1613/4885 |
| US-20130253203-A1 | Methods for Preparing Polymeric Reagents and Compositions of Polymeric Reagents | SI, PHYKPL, PHOSPHO1 | KDM4E 1654/4885LMNA 745/4885TP53 1613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.