Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850834 | 0.92 | NTRK1 (0.45) | MAPTPPARGS1PR4PTGS2NPBWR1 | |
| SCHEMBL2850809 | 0.91 | MAPT (0.43) | MAPTTSHRHTTNPSR1KMT2A | |
| SCHEMBL2852353 | 0.91 | RAB9A (0.44) | MAPTHTTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2852121 | 0.89 | P2RX7 (0.43) | MAPTNPBWR1MCHR1NPSR1MEN1 | |
| SCHEMBL2858533 | 0.85 | ATM (0.47) | MAPTPTGS2NPBWR1PTGS1TSHR | |
| SCHEMBL2859508 | 0.85 | CYP1A2 (0.46) | MAPTPKMHTTCYP1A2CYP3A4 | |
| SCHEMBL2853465 | 0.85 | RAB9A (0.44) | MAPTHTTNPSR1ALDH1A1HPGD | |
| SCHEMBL2858311 | 0.84 | RAB9A (0.47) | MAPTTSHRHTTCYP3A4CYP2C9 | |
| SCHEMBL2857582 | 0.83 | MAPT (0.42) | MAPTNPBWR1PKMMCHR1NPSR1 | |
| SCHEMBL2858283 | 0.82 | MAPT (0.43) | MAPTNPSR1KMT2ANR3C1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |