Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8338900 | 1.00 | GABRA5 (0.45) | GABRA5FFAR1ALDH1A1KDM4EFOLH1 | |
| SCHEMBL8338895 | 0.90 | GABRA5 (0.42) | GABRA5FFAR1ALDH1A1KDM4EFOLH1 | |
| SCHEMBL2851880 | 0.90 | GABRA5 (0.42) | GABRA5FFAR1ALDH1A1KDM4EFOLH1 | |
| SCHEMBL2851872 | 0.90 | GABRA5 (0.42) | GABRA5FFAR1ALDH1A1KDM4EFOLH1 | |
| SCHEMBL203005 | 0.83 | GABRA5 (0.42) | GABRA5FFAR1ALDH1A1KDM4EFOLH1 | |
| SCHEMBL8724339 | 0.82 | GABRA5 (0.40) | GABRA5FFAR1ALDH1A1FOLH1SMN1; SMN2 | |
| SCHEMBL203004 | 0.81 | SMN1; SMN2 (0.39) | GABRA5KDM4ELMNASMN1; SMN2TP53 | |
| SCHEMBL31289594 | 0.81 | SMN1; SMN2 (0.39) | GABRA5KDM4ELMNASMN1; SMN2TP53 | |
| SCHEMBL29358985 | 0.81 | SMN1; SMN2 (0.39) | GABRA5KDM4ELMNASMN1; SMN2TP53 | |
| SCHEMBL203006 | 0.80 | KDM4E (0.40) | GABRA5FFAR1ALDH1A1KDM4EFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043600-B2 | Microbiocidal compounds | SYNGENTA CROP PROTECTION AG (CH) | 2024-07-23 | — | — | US | disclosed |
| US-12012399-B2 | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2024-06-18 | — | — | US | disclosed |
| US-20240041028-A1 | DELIVERY SYSTEM FOR PLANT PROTECTION | OMYA INTERNATIONAL AG (CH) | 2024-02-08 | — | — | US | disclosed |
| US-11882834-B2 | Microbiocidal thiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2024-01-30 | — | — | US | disclosed |
| EP-4271185-A1 | DELIVERY SYSTEM FOR PLANT PROTECTION | Omya International AG (CH) | 2023-11-08 | — | — | EP | disclosed |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | SYNGENTA PARTICIPATIONS AG (CH) | 2023-09-05 | — | — | US | disclosed |
| EP-3717479-B1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-07-05 | — | — | EP | disclosed |
| EP-3941898-B1 | FUNGICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| EP-3244732-B1 | USE OF SURFACE-REACTED CALCIUM CARBONATE AS CARRIER FOR AGROCHEMICAL COMPOUNDS | OMYA INT AG (CH) | 2023-05-03 | — | — | EP | disclosed |
| US-11629138-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| US-7001903-B2 | Synergistic insecticidal mixtures | BAYER AKTIENGESELLSCHAFT (DE) | 2006-02-21 | — | — | US | disclosed |
| US-20050187215-A1 | synergistic mixture of certain previously disclosed cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-08-25 | — | — | US | disclosed |
| US-6893651-B1 | Synergistic combination of cyclic ketoenol with agonists or antagonists of nicotinic acetylcholine receptors; protecting plants | BAYER AKTIENGESELLSCHAFT (DE) | 2005-05-17 | — | — | US | disclosed |
| US-6846777-B2 | Synergistic biocidal composition | THOR GMBH (DE) | 2005-01-25 | — | — | US | disclosed |
| US-20040127520-A1 | Synergistic insecticidal mixtures | DOW AGROSCIENCES LLC | 2004-07-01 | — | — | US | disclosed |
| US-6686387-B2 | SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS; PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | disclosed |
| US-20030199490-A1 | Synergistic biocidal composition | THOR GMBH (DE) | 2003-10-23 | — | — | US | disclosed |
| US-20030092641-A1 | Synergistic insecticidal mixtures | DOW AGROSCIENCES LLC | 2003-05-15 | — | — | US | disclosed |
| US-6444667-B1 | OF SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS FOR PROTECTING PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| US-5466693-A | FOE USE IN THE CULTIVATION OF RICE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092641-A1 | Synergistic insecticidal mixtures | CHRM3, ACHE, CHRM2 | GABRA5 370/4885FFAR1 942/4885ALDH1A1 4569/4885 |
| US-12043600-B2 | Microbiocidal compounds | MPO, MSR1, PRF1 | GABRA5 2323/4885FFAR1 492/4885ALDH1A1 500/4885 |
| US-20040127520-A1 | Synergistic insecticidal mixtures | CHRM3, ACHE, CHRM2 | GABRA5 370/4885FFAR1 942/4885ALDH1A1 4569/4885 |
| US-11882834-B2 | Microbiocidal thiazole derivatives | MSR1, TLR1, IFNG | GABRA5 2564/4885FFAR1 648/4885ALDH1A1 392/4885 |
| US-12012399-B2 | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives | TLR1, TLR5, IDO1 | GABRA5 3613/4885FFAR1 1006/4885ALDH1A1 312/4885 |
| US-20050187215-A1 | synergistic mixture of certain previously disclosed cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors | CHRNG, CHRM3, CHRNE | GABRA5 201/4885FFAR1 132/4885ALDH1A1 2646/4885 |
| US-11629138-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, FPR1 | GABRA5 2332/4885FFAR1 169/4885ALDH1A1 1067/4885 |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | PHF20, FUCA1, ZP1 | GABRA5 3848/4885FFAR1 783/4885ALDH1A1 1241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.