Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.37 |
| ▸ | CD38 | P28907 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | GPX4 | P36969 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857917 | 0.88 | MAPT (0.42) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL2854810 | 0.86 | KMT2A (0.46) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL2862993 | 0.86 | MEN1 (0.41) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL2852553 | 0.86 | MALT1 (0.40) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL2854572 | 0.85 | RAB9A (0.44) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL2854269 | 0.84 | RAB9A (0.46) | MAPTRAB9ANPC1MTORALDH1A1 | |
| SCHEMBL2856974 | 0.83 | MAPT (0.39) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL2857337 | 0.83 | KMT2A (0.43) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL2852401 | 0.80 | L3MBTL1 (0.39) | MEN1KMT2ANPSR1L3MBTL1RAB9A | |
| SCHEMBL2861646 | 0.80 | NPC1 (0.42) | MAPTMEN1KMT2AKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |