Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | VEGFA | P15692 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | STK10 | O94804 | 1/20 | 0.38 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | PYGM | P11217 | 1/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852472 | 0.90 | KDM4E (0.41) | KDM4EPOLBCTNNB1ALOX5EPAS1 | |
| SCHEMBL30051463 | 0.90 | KDM4E (0.41) | KDM4EPOLBCTNNB1ALOX5EPAS1 | |
| SCHEMBL2852480 | 0.90 | KDM4E (0.41) | KDM4EPOLBCTNNB1ALOX5EPAS1 | |
| SCHEMBL204999 | 0.83 | KDM4E (0.40) | KDM4EPOLBCTNNB1ALOX5EPAS1 | |
| SCHEMBL2855939 | 0.82 | KDM4E (0.59) | KDM4EPOLBCTNNB1HTTPGR | |
| SCHEMBL2107594 | 0.82 | KDM4E (0.59) | KDM4EPOLBCTNNB1HTTPGR | |
| SCHEMBL851003 | 0.82 | HTT (0.51) | KDM4EPOLBCTNNB1EPAS1VEGFA | |
| SCHEMBL29356020 | 0.82 | AR (0.38) | KDM4EPOLBEPAS1VEGFAAR | |
| SCHEMBL204998 | 0.82 | AR (0.38) | KDM4EPOLBEPAS1VEGFAAR | |
| SCHEMBL205000 | 0.81 | KDM4E (0.41) | KDM4EPOLBHTTARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043600-B2 | Microbiocidal compounds | SYNGENTA CROP PROTECTION AG (CH) | 2024-07-23 | — | — | US | disclosed |
| US-12012399-B2 | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2024-06-18 | — | — | US | disclosed |
| US-20240041028-A1 | DELIVERY SYSTEM FOR PLANT PROTECTION | OMYA INTERNATIONAL AG (CH) | 2024-02-08 | — | — | US | disclosed |
| US-11882834-B2 | Microbiocidal thiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2024-01-30 | — | — | US | disclosed |
| EP-4271185-A1 | DELIVERY SYSTEM FOR PLANT PROTECTION | Omya International AG (CH) | 2023-11-08 | — | — | EP | disclosed |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | SYNGENTA PARTICIPATIONS AG (CH) | 2023-09-05 | — | — | US | disclosed |
| EP-3717479-B1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-07-05 | — | — | EP | disclosed |
| EP-3941898-B1 | FUNGICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| EP-3244732-B1 | USE OF SURFACE-REACTED CALCIUM CARBONATE AS CARRIER FOR AGROCHEMICAL COMPOUNDS | OMYA INT AG (CH) | 2023-05-03 | — | — | EP | disclosed |
| US-11629129-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| US-7001903-B2 | Synergistic insecticidal mixtures | BAYER AKTIENGESELLSCHAFT (DE) | 2006-02-21 | — | — | US | disclosed |
| US-20050187215-A1 | synergistic mixture of certain previously disclosed cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-08-25 | — | — | US | disclosed |
| US-6846777-B2 | Synergistic biocidal composition | THOR GMBH (DE) | 2005-01-25 | — | — | US | disclosed |
| US-20040127520-A1 | Synergistic insecticidal mixtures | DOW AGROSCIENCES LLC | 2004-07-01 | — | — | US | disclosed |
| US-6686387-B2 | SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS; PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | disclosed |
| US-20030199490-A1 | Synergistic biocidal composition | THOR GMBH (DE) | 2003-10-23 | — | — | US | disclosed |
| US-20030092641-A1 | Synergistic insecticidal mixtures | DOW AGROSCIENCES LLC | 2003-05-15 | — | — | US | disclosed |
| US-6444667-B1 | OF SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS FOR PROTECTING PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| US-5972971-A | WOOD PRESERVATIVE CONSISTS OF A MIXTURE OF METACONAZOLE OR AN ACID ADDITION SALT OR METAL COMPLEX AND IMIDACLOPRID OR SALT OR METAL COMPLEX | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-26 | — | — | US | disclosed |
| US-5466693-A | FOE USE IN THE CULTIVATION OF RICE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092641-A1 | Synergistic insecticidal mixtures | CHRM3, ACHE, CHRM2 | KDM4E 3852/4885POLB 4880/4885CTNNB1 3858/4885 |
| US-12043600-B2 | Microbiocidal compounds | MPO, MSR1, PRF1 | KDM4E 2462/4885POLB 3401/4885CTNNB1 4410/4885 |
| US-20040127520-A1 | Synergistic insecticidal mixtures | CHRM3, ACHE, CHRM2 | KDM4E 3852/4885POLB 4880/4885CTNNB1 3858/4885 |
| US-11882834-B2 | Microbiocidal thiazole derivatives | MSR1, TLR1, IFNG | KDM4E 3260/4885POLB 3655/4885CTNNB1 4135/4885 |
| US-12012399-B2 | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives | TLR1, TLR5, IDO1 | KDM4E 2885/4885POLB 2340/4885CTNNB1 2621/4885 |
| US-20050187215-A1 | synergistic mixture of certain previously disclosed cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors | CHRNG, CHRM3, CHRNE | KDM4E 1928/4885POLB 4609/4885CTNNB1 4413/4885 |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | PHF20, FUCA1, ZP1 | KDM4E 4050/4885POLB 4375/4885CTNNB1 4851/4885 |
| US-11629129-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, MSR1 | KDM4E 3192/4885POLB 3215/4885CTNNB1 4671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.