Sugi Predict

Sugi Predict / Compounds / SCHEMBL205000

SCHEMBL205000

SCHEMBL205000

COC(C)=C(C(=O)O)c1ccccc1Oc1cccc(Oc2cccc(C#N)c2)c1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ MTNR1B P49286 1/20 0.40
▸ PYGL P06737 1/20 0.40
▸ PYGM P11217 1/20 0.40
▸ CCR2 P41597 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ AR P10275 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ PGR P06401 1/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ RXFP1 Q9HBX9 1/20 0.38
▸ STK10 O94804 1/20 0.38
▸ SLK Q9H2G2 1/20 0.38
▸ PTGER4 P35408 1/20 0.38
▸ PTGER2 P43116 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7621992 1.00 KDM4E (0.41) KDM4EPOLBMTNR1BPYGLPYGM
SCHEMBL204999 0.90 KDM4E (0.40) KDM4EPOLBPYGLPYGMHTT
SCHEMBL202626 0.85 KDM4E (0.57) KDM4EPOLBMTNR1BPYGMRAB9A
SCHEMBL203718 0.82 CTNNB1 (0.54) KDM4EHTTRAB9AMEN1KMT2A
SCHEMBL203989 0.81 KDM4E (0.44) KDM4EPOLBMTNR1BHTTRAB9A
SCHEMBL204355 0.81 L3MBTL1 (0.44) KDM4EPOLBMTNR1BRAB9AMEN1
SCHEMBL18772927 0.81 AR (0.45) KDM4EPOLBHTTARRAB9A
SCHEMBL203538 0.81 LMNA (0.51) KDM4EPOLBMTNR1BRAB9ASMN1; SMN2
SCHEMBL2852479 0.81 KDM4E (0.40) KDM4EPOLBPYGLPYGMHTT
SCHEMBL9155384 0.80 SIRT2 (0.47) KDM4EPOLBMTNR1BHTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 — — US disclosed
US-20250241304-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 — — US disclosed
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 — — US disclosed
US-20150144027-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) 2015-05-28 — — US disclosed
US-8871277-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2014-10-28 — — US disclosed
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF AVENTIS AGRICULTURE (FR) 2013-12-05 — — US disclosed
US-20130230575-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME OSMOSE, INC. (US) 2013-09-05 — — US disclosed
US-8445519-B2 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof AVENTIS AGRICULTURE (FR) 2013-05-21 — — US disclosed
US-8409627-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2013-04-02 — — US disclosed
US-8088801-B2 Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof MERIAL LIMITED (US) 2012-01-03 — — US disclosed
EP-0730517-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AG (DE) 1996-09-11 — — EP disclosed
WO-1996025044-A1 S-ARYL CYANIMIDOTHIO COMPOUNDS FOR MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1996-08-22 — — WO disclosed
EP-0714420-A1 MOULD-RESISTANT EMULSION PAINTS BAYER AG (DE) 1996-06-05 — — EP disclosed
WO-1996010915-A1 INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-04-18 — — WO disclosed
EP-0705160-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AG (DE) 1996-04-10 — — EP disclosed
WO-1995034204-A1 BACTERICIDE THIADIAZOLIDINONES BAYER AKTIENGESELLSCHAFT (DE) 1995-12-21 — — WO disclosed
WO-1995024997-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 1995-09-21 — — WO disclosed
WO-1995014558-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-06-01 — — WO disclosed
WO-1995006091-A1 MOULD-RESISTANT EMULSION PAINTS BAYER AKTIENGESELLSCHAFT (DE) 1995-03-02 — — WO disclosed
WO-1995000303-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 KDM4E 1828/4885POLB 1822/4885MTNR1B 1812/4885
US-20250241304-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 KDM4E 852/4885POLB 4747/4885MTNR1B 1292/4885
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF CBR3, CBR1, NR5A2 KDM4E 3120/4885POLB 4213/4885MTNR1B 510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.