SCHEMBL384014

SCHEMBL384014

O=C(Cl)OB(O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ORAI1 Q96D31 3/20 0.42
ORAI2 Q96SN7 3/20 0.42
ORAI3 Q9BRQ5 3/20 0.42
TRPV6 Q9H1D0 3/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
ENPP2 Q13822 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
PCSK9 Q8NBP7 1/20 0.42
ALDH1A1 P00352 5/20 0.41
CES2 O00748 3/20 0.33
CES1 P23141 3/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
MGLL Q99685 2/20 0.33
LMNA P02545 2/20 0.33
AKR1B1 P15121 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1672441 0.82 ORAI1 (0.46) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL384013 0.80 ORAI1 (0.42) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL28664851 0.80 TRPV6 (0.44) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL56273 0.78 ORAI1 (0.42) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL20916961 0.78 LMNA (0.54) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL651370 0.78 ORAI1 (0.42) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL27008267 0.77 TRPV6 (0.41) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL1237453 0.75 KMT2A (0.42) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL1789520 0.74 PKM (0.42) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL5951647 0.74 ELANE (0.46) ORAI1ORAI2ORAI3TRPV6CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119752437-A Organic electroluminescent material containing double main bodies, preparation method and application thereof 吉林奥来德光电材料股份有限公司 2025-04-04 CN claimed
CN-119775266-A Organic electroluminescent compound, organic electroluminescent material containing double bodies, and light-emitting device 吉林奥来德光电材料股份有限公司 2025-04-08 CN disclosed
CN-119752437-A Organic electroluminescent material containing double main bodies, preparation method and application thereof 吉林奥来德光电材料股份有限公司 2025-04-04 CN disclosed
EP-2408729-B1 NOVEL BICHRYSENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND CANON KK (JP) 2015-12-16 EP disclosed
US-8580400-B2 Bichrysene compound and organic light emitting device having the compound CANON KABUSHIKI KAISHA (JP) 2013-11-12 US disclosed
EP-2408729-A1 NOVEL BICHRYSENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND Canon Kabushiki Kaisha (JP) 2012-01-25 EP disclosed
US-20110272683-A1 NOVEL BICHRYSENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2011-11-10 US disclosed
WO-2010107097-A1 NOVEL BICHRYSENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2010-09-23 WO disclosed
EP-1539158-A1 ARYL PIPERIDINE DERIVATIVES AS INDUCERS OF LDL-RECEPTOR EXPRESSION FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA GLAXO GROUP LIMITED (GB) 2005-06-15 EP disclosed
WO-2004006922-A1 ARYL PIPERIDINE DERIVATIVES AS INDUCERS OF LDL-RECEPTOR EXPRESSION FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA GLAXO GROUP LIMITED (GB) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110272683-A1 NOVEL BICHRYSENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND PPOX, CRY1, OXER1 ORAI1 935/4885ORAI2 235/4885ORAI3 473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.