Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860499 | 0.91 | RAB9A (0.35) | CNR2DRD2MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2862815 | 0.87 | DRD2 (0.41) | DRD2MAPTPOLBSMN1; SMN2KDM4E | |
| SCHEMBL2856129 | 0.85 | DRD2 (0.35) | CNR2DRD2MAPTCNR1MAPK1 | |
| SCHEMBL2859870 | 0.85 | TLR7 (0.38) | MAPTPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2854040 | 0.81 | KDM4E (0.48) | MAPTPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2900711 | 0.76 | MAPT (0.40) | MAPTPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2854678 | 0.76 | ATR (0.40) | MAPTKDM4ECYP2C9 | |
| SCHEMBL2857444 | 0.74 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1TSHRMAPK1 | |
| SCHEMBL2858340 | 0.74 | MALT1 (0.42) | CNR2DRD2 | |
| SCHEMBL2861607 | 0.74 | TRPV1 (0.42) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |