Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859870 | 0.89 | TLR7 (0.38) | MAPTPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2854514 | 0.87 | CNR2 (0.35) | DRD2MAPTPOLBSMN1; SMN2KDM4E | |
| SCHEMBL2860499 | 0.86 | RAB9A (0.35) | DRD2MAPTPOLBSMN1; SMN2KDM4E | |
| SCHEMBL2856129 | 0.85 | DRD2 (0.35) | DRD2MAPTMALT1MAPK1CNR1 | |
| SCHEMBL2860428 | 0.83 | KDM4E (0.52) | MAPTPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2859419 | 0.83 | CYP3A4 (0.45) | MAPTPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2858119 | 0.82 | MAPT (0.43) | DRD2MAPTPOLBSMN1; SMN2KDM4E | |
| SCHEMBL2854676 | 0.81 | ALDH1A1 (0.45) | MAPTSMN1; SMN2KDM4EALDH1A1MALT1 | |
| SCHEMBL2848353 | 0.79 | SMN1; SMN2 (0.48) | MAPTPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2848317 | 0.79 | MAPT (0.46) | MAPTPOLBSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |