Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 8/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860499 | 0.90 | RAB9A (0.35) | DRD2KEAP1NFE2L2CNR2CNR1 | |
| SCHEMBL2854514 | 0.85 | CNR2 (0.35) | DRD2CNR2CNR1S1PR2S1PR4 | |
| SCHEMBL2855566 | 0.85 | MALT1 (0.44) | MALT1MAPT | |
| SCHEMBL2862815 | 0.85 | DRD2 (0.41) | DRD2MALT1CNR1MAPK1MAPT | |
| SCHEMBL2859870 | 0.80 | TLR7 (0.38) | MAPK1MAPT | |
| SCHEMBL2852553 | 0.78 | MALT1 (0.40) | KEAP1NFE2L2MALT1MAPT | |
| SCHEMBL2850882 | 0.77 | MALT1 (0.44) | MALT1 | |
| SCHEMBL2852401 | 0.76 | L3MBTL1 (0.39) | — | |
| SCHEMBL2852387 | 0.76 | P2RX7 (0.37) | KEAP1NFE2L2MALT1MAPT | |
| SCHEMBL2854492 | 0.74 | MAPT (0.42) | MALT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |