Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.48 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.48 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.48 |
| ▸ | ALOX5AP known ✓ | P20292 | 1/20 | 0.48 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | MB | P02144 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11804738 | 0.97 | SMN1; SMN2 (0.66) | SMN1; SMN2POLBPKMKDM4ETDP1 | |
| SCHEMBL11313280 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBPKMKDM4ETDP1 | |
| SCHEMBL2345862 | 0.84 | TDP1 (0.49) | SMN1; SMN2POLBPKMKDM4ETDP1 | |
| SCHEMBL1258654 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2POLBPKMKDM4ETDP1 | |
| SCHEMBL31254026 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2POLBPKMKDM4ETDP1 | |
| SCHEMBL11800293 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBPKMKDM4ETDP1 | |
| SCHEMBL729994 | 0.82 | SMN1; SMN2 (0.70) | SMN1; SMN2POLBPKMKDM4ETDP1 | |
| SCHEMBL11804736 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2POLBPKMKDM4ETDP1 | |
| SCHEMBL11796153 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBKDM4ETDP1ALDH1A1 | |
| SCHEMBL2127575 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2POLBPKMKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114317842-B | Manufacturing process of flame-retardant anti-sticking low-VOC automobile cushion leather | 江苏科美新材料有限公司 | 2023-09-08 | — | — | CN | claimed |
| CN-113755088-B | Preparation method of substances required by preparation method of flame-retardant wear-resistant low-VOC (volatile organic compound) polyurethane coating | 烟台大学 | 2022-04-15 | — | — | CN | claimed |
| CN-114317842-B | Manufacturing process of flame-retardant anti-sticking low-VOC automobile cushion leather | 江苏科美新材料有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-113755088-B | Preparation method of substances required by preparation method of flame-retardant wear-resistant low-VOC (volatile organic compound) polyurethane coating | 烟台大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-114317842-A | Key material for manufacturing process of flame-retardant anti-adhesion low-VOC (volatile organic compound) automobile cushion leather | 烟台大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-112708706-B | Manufacturing process of flame-retardant, wear-resistant, anti-sticking and low-VOC (volatile organic compound) automobile cushion leather | 烟台大学 | 2022-01-25 | — | — | CN | disclosed |
| CN-113755088-A | Preparation method of substances required by preparation method of flame-retardant wear-resistant low-VOC (volatile organic compound) polyurethane coating | 烟台大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-112646475-B | Preparation and application methods of flame-retardant wear-resistant low-VOC (volatile organic compound) polyurethane coating | 烟台大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-112708706-A | Manufacturing process of flame-retardant, wear-resistant, anti-sticking and low-VOC (volatile organic compound) automobile cushion leather | 烟台大学 | 2021-04-27 | — | — | CN | disclosed |
| CN-112646475-A | Preparation and application methods of flame-retardant wear-resistant low-VOC (volatile organic compound) polyurethane coating | 烟台大学 | 2021-04-13 | — | — | CN | disclosed |