Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of N-Methylpiperidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 2/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Methyl Pyrrolidine (Nmp) SCHEMBL28445263 | 0.98 | DNM1 (0.52) | DNM1MEN1KMT2AALDH1A1TSHR | |
| N-Methylpiperidine SCHEMBL23198385 | 0.89 | L3MBTL1 (0.45) | MEN1KMT2ATSHRTDP1L3MBTL1 | |
| N-Methylpiperidine SCHEMBL29259680 | 0.89 | L3MBTL1 (0.45) | MEN1KMT2ATSHRTDP1L3MBTL1 | |
| N-Methylpiperidine SCHEMBL28251315 | 0.89 | L3MBTL1 (0.45) | MEN1KMT2ATSHRTDP1L3MBTL1 | |
| N-Methylpiperidine SCHEMBL28080302 | 0.86 | DNM1 (0.42) | DNM1MEN1KMT2ATSHR | |
| Heptane SCHEMBL23198384 | 0.86 | GNAI3 (0.45) | MEN1KMT2ATSHRTDP1L3MBTL1 | |
| N-Methylpiperidine SCHEMBL20503132 | 0.86 | L3MBTL1 (0.46) | MEN1KMT2ATSHRTDP1L3MBTL1 | |
| N-Methylpiperidine SCHEMBL28259487 | 0.86 | L3MBTL1 (0.46) | MEN1KMT2ATSHRTDP1L3MBTL1 | |
| Hexane SCHEMBL28381606 | 0.86 | GNAI3 (0.43) | MEN1KMT2AALDH1A1TSHRTDP1 | |
| N-Methylpiperidine SCHEMBL23198382 | 0.84 | L3MBTL1 (0.40) | MEN1KMT2AALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112591760-B | SSZ-16 molecular sieve with new morphology synthesized by Y molecular sieve crystal transformation and method thereof | 金华职业技术学院 | 2022-06-17 | — | — | CN | claimed |
| CN-112591760-A | SSZ-16 molecular sieve with new morphology synthesized by Y molecular sieve crystal transformation and method thereof | 金华职业技术学院 | 2021-04-02 | — | — | CN | claimed |
| CN-114210363-B | Preparation method of SSZ-16 copper-containing catalyst | 天津派森新材料技术有限责任公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-112591760-B | SSZ-16 molecular sieve with new morphology synthesized by Y molecular sieve crystal transformation and method thereof | 金华职业技术学院 | 2022-06-17 | — | — | CN | disclosed |
| CN-114210363-A | Preparation method of SSZ-16 copper-containing catalyst | 天津派森新材料技术有限责任公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-112591760-A | SSZ-16 molecular sieve with new morphology synthesized by Y molecular sieve crystal transformation and method thereof | 金华职业技术学院 | 2021-04-02 | — | — | CN | disclosed |