Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861180 | 0.85 | MMP13 (0.46) | ALDH1A1 | |
| SCHEMBL2851648 | 0.84 | ALDH1A1 (0.51) | GAAALDH1A1HTTL3MBTL1NPSR1 | |
| SCHEMBL2857248 | 0.82 | CARM1 (0.39) | ALDH1A1 | |
| SCHEMBL2856257 | 0.78 | NPC1 (0.50) | APEX1NPC1RAB9AALDH1A1PLA2G1B | |
| SCHEMBL2854435 | 0.77 | TSHR (0.48) | GAANPC1RAB9AALDH1A1PLA2G1B | |
| SCHEMBL2858150 | 0.76 | LMNA (0.52) | GAANPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL8765259 | 0.75 | GAA (0.53) | GAAAPEX1NPC1RAB9AALDH1A1 | |
| SCHEMBL2852748 | 0.74 | GRM5 (0.40) | — | |
| SCHEMBL2857323 | 0.73 | CA12 (0.45) | APEX1PLA2G1BHTTL3MBTL1ATG4B | |
| SCHEMBL4966958 | 0.73 | EPHX2 (0.44) | APEX1NPC1RAB9AALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963277-B1 | FLUORINATED COMPOUNDS | NPS PHARMA INC (US) | 2010-01-20 | — | — | EP | claimed |
| EP-1963277-B1 | FLUORINATED COMPOUNDS | NPS PHARMA INC (US) | 2010-01-20 | — | — | EP | disclosed |