Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858150 | 0.87 | LMNA (0.52) | HPGDLMNAMEN1KMT2AGAA | |
| SCHEMBL2851648 | 0.87 | ALDH1A1 (0.51) | TSHRHPGDLMNAMEN1KMT2A | |
| SCHEMBL2857248 | 0.85 | CARM1 (0.39) | ALDH1A1MAOB | |
| SCHEMBL2852748 | 0.79 | GRM5 (0.40) | HPGDLMNA | |
| SCHEMBL2861180 | 0.77 | MMP13 (0.46) | HPGDKMT2AALDH1A1TP53 | |
| SCHEMBL2856255 | 0.77 | GAA (0.48) | GAAALDH1A1HTTL3MBTL1PLA2G1B | |
| SCHEMBL2854437 | 0.75 | LMNA (0.64) | HPGDLMNAKMT2AGAAALDH1A1 | |
| SCHEMBL2849991 | 0.73 | RECQL (0.51) | TSHRHPGDLMNAMEN1KMT2A | |
| SCHEMBL5071229 | 0.73 | TGM2 (0.69) | HPGDLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL28853573 | 0.73 | LMNA (0.56) | HPGDLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963277-B1 | FLUORINATED COMPOUNDS | NPS PHARMA INC (US) | 2010-01-20 | — | — | EP | claimed |
| EP-1963277-B1 | FLUORINATED COMPOUNDS | NPS PHARMA INC (US) | 2010-01-20 | — | — | EP | disclosed |