Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Pyrrolidone SCHEMBL933908 | 0.87 | OR51E2 (0.50) | OR51E2FKBP5CRBN | |
| 2-Pyrrolidone SCHEMBL4595907 | 0.85 | OR51E2 (0.52) | OR51E2FKBP5CRBN | |
| 2-Pyrrolidone SCHEMBL22534 | 0.85 | OR51E2 (0.52) | OR51E2FKBP5CRBN | |
| 2-Pyrrolidone SCHEMBL28565455 | 0.84 | OR51E2 (0.50) | OR51E2FKBP5CRBN | |
| 2-Pyrrolidone SCHEMBL27876042 | 0.81 | OR51E2 (0.47) | OR51E2FKBP5CRBN | |
| Itaconate SCHEMBL2441529 | 0.81 | ALOX15 (0.59) | ALOX15HSD17B10 | |
| 2-Pyrrolidone SCHEMBL852356 | 0.80 | OR51E2 (0.43) | OR51E2FKBP5CRBN | |
| Caprolactam SCHEMBL28156132 | 0.78 | FKBP5 (0.46) | OR51E2FKBP5CRBN | |
| Itaconate SCHEMBL128186 | 0.76 | ALOX15 (0.38) | ALOX15HSD17B10 | |
| 2-Pyrrolidone SCHEMBL27365042 | 0.76 | OR51E2 (0.47) | OR51E2FKBP5CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080206164-A1 | Cosmetic composition comprising at least one cationic polyurethane and at least one vinyl pyrrolidone homo- or copolymer, and method of styling therewith | L'OREAL S.A. (FR) | 2008-08-28 | — | — | US | claimed |
| US-20080206164-A1 | Cosmetic composition comprising at least one cationic polyurethane and at least one vinyl pyrrolidone homo- or copolymer, and method of styling therewith | L'OREAL S.A. (FR) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080206164-A1 | Cosmetic composition comprising at least one cationic polyurethane and at least one vinyl pyrrolidone homo- or copolymer, and method of styling therewith | PUF60, SRSF2, PCBP1 | ALOX15 41/4885HSD17B10 922/4885OR51E2 1565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.