Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Pyrrolidone SCHEMBL28279632 | 0.94 | OR51E2 (0.48) | OR51E2FKBP5CRBNTSHRUSP2 | |
| 2-Pyrrolidone SCHEMBL22534 | 0.91 | OR51E2 (0.52) | OR51E2FKBP5CRBNALDH1A1 | |
| 2-Pyrrolidone SCHEMBL4595907 | 0.91 | OR51E2 (0.52) | OR51E2FKBP5CRBNALDH1A1 | |
| 2-Pyrrolidone SCHEMBL28565455 | 0.90 | OR51E2 (0.50) | OR51E2FKBP5CRBN | |
| 2-Pyrrolidone SCHEMBL933908 | 0.90 | OR51E2 (0.50) | OR51E2FKBP5CRBN | |
| 2-Pyrrolidone SCHEMBL27876042 | 0.87 | OR51E2 (0.47) | OR51E2FKBP5CRBN | |
| Caprolactam SCHEMBL28156132 | 0.83 | FKBP5 (0.46) | OR51E2FKBP5CRBN | |
| Itaconate SCHEMBL4960729 | 0.80 | ALOX15 (0.40) | OR51E2FKBP5CRBN | |
| SCHEMBL5045890 | 0.79 | ALDH1A1 (0.37) | TSHRALDH1A1TDP1 | |
| 2-Pyrrolidone SCHEMBL2110293 | 0.79 | OR51E2 (0.48) | OR51E2FKBP5CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080206164-A1 | Cosmetic composition comprising at least one cationic polyurethane and at least one vinyl pyrrolidone homo- or copolymer, and method of styling therewith | L'OREAL S.A. (FR) | 2008-08-28 | — | — | US | claimed |
| CN-104066419-B | Method for treating straightened keratin fibers | 莱雅公司 | 2018-05-08 | — | — | CN | disclosed |
| EP-2662400-B1 | Block type-modified organopolysiloxane, method for using the organopolysiloxane, cosmetic, and method for producing the organopolysiloxane | SHINETSU CHEMICAL CO (JP) | 2017-09-13 | — | — | EP | disclosed |
| US-9078836-B2 | Block type-modified organopolysiloxane, method for using the organopolysiloxane, cosmetic, and method for producing the organopolysiloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-07-14 | — | — | US | disclosed |
| US-20130302263-A1 | BLOCK TYPE-MODIFIED ORGANOPOLYSILOXANE, METHOD FOR USING THE ORGANOPOLYSILOXANE, COSMETIC, AND METHOD FOR PRODUCING THE ORGANOPOLYSILOXANE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-11-14 | — | — | US | disclosed |
| EP-2662400-A2 | Block type-modified organopolysiloxane, method for using the organopolysiloxane, cosmetic, and method for producing the organopolysiloxane | Shin-Etsu Chemical Co., Ltd. (JP) | 2013-11-13 | — | — | EP | disclosed |
| WO-2012065971-A9 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE ELASTOMERIC POLYURETHANE AND AT LEAST ONE CATIONIC POLYMER | L'OREAL (FR) | 2013-10-24 | — | — | WO | disclosed |
| WO-2012065971-A2 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE ELASTOMERIC POLYURETHANE AND AT LEAST ONE CATIONIC POLYMER | L'OREAL (FR) | 2012-05-24 | — | — | WO | disclosed |
| EP-2432448-A2 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE ELASTOMERIC POLYURETHANE | L'Oréal (FR) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133660-A2 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE ELASTOMERIC POLYURETHANE | L'OREAL (FR) | 2010-11-25 | — | — | WO | disclosed |
| US-20080206164-A1 | Cosmetic composition comprising at least one cationic polyurethane and at least one vinyl pyrrolidone homo- or copolymer, and method of styling therewith | L'OREAL S.A. (FR) | 2008-08-28 | — | — | US | disclosed |
| US-20060177399-A1 | Pressurized device for hair fiber styling and use of the same for hair fiber styling and/or hair | L'OREAL S.A. (FR) | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130302263-A1 | BLOCK TYPE-MODIFIED ORGANOPOLYSILOXANE, METHOD FOR USING THE ORGANOPOLYSILOXANE, COSMETIC, AND METHOD FOR PRODUCING THE ORGANOPOLYSILOXANE | H1-0, H1-4, H1-2 | OR51E2 934/4885FKBP5 3346/4885CRBN 1034/4885 |
| US-20080206164-A1 | Cosmetic composition comprising at least one cationic polyurethane and at least one vinyl pyrrolidone homo- or copolymer, and method of styling therewith | PUF60, SRSF2, PCBP1 | OR51E2 1565/4885FKBP5 115/4885CRBN 4285/4885 |
| US-20060177399-A1 | Pressurized device for hair fiber styling and use of the same for hair fiber styling and/or hair | POLR1C, NACA, SHH | OR51E2 270/4885FKBP5 168/4885CRBN 3340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.