Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852547 | 0.81 | LMNA (0.45) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL2856900 | 0.80 | MAPT (0.47) | SMN1; SMN2MAPTGAACYP1A2CYP2D6 | |
| SCHEMBL2852375 | 0.79 | CCR1 (0.63) | MEN1KMT2AMAPTHPGDGAA | |
| SCHEMBL2851002 | 0.79 | SMN1; SMN2 (0.53) | L3MBTL1SMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL2848480 | 0.78 | ALDH1A1 (0.61) | L3MBTL1SMN1; SMN2ALDH1A1HTTKDM4E | |
| SCHEMBL2857766 | 0.78 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL2858349 | 0.78 | CNR1 (0.44) | ALDH1A1MAPTGAALMNA | |
| SCHEMBL2850782 | 0.77 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL2855797 | 0.77 | CNR1 (0.47) | SMN1; SMN2MAPTGAANPSR1LMNA | |
| SCHEMBL2856558 | 0.77 | LMNA (0.48) | ALDH1A1KMT2AMAPTHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |