Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851002 | 0.90 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2TP53HPGDHTT | |
| SCHEMBL2848480 | 0.90 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2TSHRKDM4EMAPT | |
| SCHEMBL2863326 | 0.88 | TP53 (0.53) | ALDH1A1SMN1; SMN2TP53THRBTSHR | |
| SCHEMBL2854531 | 0.82 | LMNA (0.52) | ALDH1A1SMN1; SMN2TP53MAPTRXFP1 | |
| SCHEMBL2854802 | 0.82 | LMNA (0.48) | ALDH1A1TP53THRBMAPTKMT2A | |
| SCHEMBL2860234 | 0.81 | HPGD (0.54) | ALDH1A1SMN1; SMN2TP53TSHRMAPT | |
| SCHEMBL2850427 | 0.79 | SMN1; SMN2 (0.60) | ALDH1A1SMN1; SMN2TP53THRBTSHR | |
| SCHEMBL2852238 | 0.78 | GAA (0.55) | SMN1; SMN2TP53THRBNPSR1KDM4E | |
| SCHEMBL2856865 | 0.78 | L3MBTL1 (0.51) | ALDH1A1SMN1; SMN2TP53THRBTSHR | |
| SCHEMBL2856388 | 0.78 | TRPV1 (0.51) | ALDH1A1SMN1; SMN2TP53THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |