SCHEMBL28577303

SCHEMBL28577303

COC(=O)[C@@H]1CC[C@@H](N(OCc2ccccc2)S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CN1C(C)=O

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.46
ANPEP P15144 1/20 0.46
MAPK1 P28482 2/20 0.43
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 3/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ATM Q13315 1/20 0.40
CCR5 P51681 5/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 1/20 0.38
FKBP1A P62942 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23668284 0.92 MAPK1 (0.43) MMP2ANPEPMAPK1TDP1ALDH1A1
SCHEMBL30695875 0.90 MAPK1 (0.41) MMP2ANPEPMAPK1TDP1ALDH1A1
SCHEMBL24142105 0.90 MAPK1 (0.43) MMP2ANPEPMAPK1TDP1ALDH1A1
SCHEMBL24142140 0.90 MAPK1 (0.43) MMP2ANPEPMAPK1TDP1ALDH1A1
SCHEMBL30695869 0.89 CCR5 (0.42) MMP2MAPK1TDP1ALDH1A1L3MBTL1
SCHEMBL24142137 0.89 MMP2 (0.46) MMP2ANPEPMAPK1TDP1ALDH1A1
SCHEMBL31294395 0.81 MAPK1 (0.43) MAPK1TDP1ALDH1A1L3MBTL1ATM
SCHEMBL24141866 0.81 MAPK1 (0.45) MAPK1TDP1ALDH1A1L3MBTL1ATM
SCHEMBL23668286 0.81 MMP1 (0.43) MMP2MAPK1TDP1ALDH1A1L3MBTL1
SCHEMBL23668279 0.81 CCR5 (0.43) MAPK1TDP1ALDH1A1ATMCCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3854786-B1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES UBE CORP (JP) 2026-02-18 EP disclosed
US-12281074-B2 Method for producing amino acid derivatives UBE CORPORATION (JP) 2025-04-22 US disclosed
US-12202800-B2 Method for producing amino acid derivatives API CORPORATION (JP) 2025-01-21 US disclosed
US-20240150292-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES API CORPORATION (JP) 2024-05-09 US disclosed
US-11897844-B2 Method for producing amino acid derivatives API CORPORATION (JP) 2024-02-13 US disclosed
US-20240002340-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES API CORPORATION (JP) 2024-01-04 US disclosed
CN-112930338-A Process for the preparation of amino acid derivatives 株式会社API 2021-06-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150292-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES PTGS2, PTGES, PTGS1 MMP2 3356/4885ANPEP 500/4885MAPK1 748/4885
US-12202800-B2 Method for producing amino acid derivatives GLO1, BCAT2, BCAT1 MMP2 2853/4885ANPEP 144/4885MAPK1 208/4885
US-20240002340-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES GLO1, BCAT2, BCAT1 MMP2 2853/4885ANPEP 144/4885MAPK1 208/4885
US-11897844-B2 Method for producing amino acid derivatives PTGS2, PTGES, PTGES2 MMP2 3155/4885ANPEP 524/4885MAPK1 770/4885
US-12281074-B2 Method for producing amino acid derivatives PTGS2, PTGES, PTGES2 MMP2 3155/4885ANPEP 524/4885MAPK1 770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.