SCHEMBL28578570

SCHEMBL28578570

COC(=O)[C@@H]1CC[C@@H](NOCc2ccccc2)CN1C(C)=O

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 10/20 0.52
FKBP1A P62942 5/20 0.44
ANPEP P15144 6/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
ACE P12821 1/20 0.40
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23668280 0.91 MMP2 (0.43) MMP2FKBP1AANPEPALDH1A1TSHR
SCHEMBL16611573 0.87 FKBP1A (0.41) MMP2FKBP1AALDH1A1CYP3A4TSHR
SCHEMBL16611571 0.87 FKBP1A (0.41) MMP2FKBP1AALDH1A1CYP3A4TSHR
SCHEMBL10139494 0.86 FKBP1A (0.43) MMP2FKBP1AALDH1A1
Hydrochloric Acid SCHEMBL16611802 0.86 FKBP1A (0.41) MMP2FKBP1AALDH1A1CYP3A4TSHR
SCHEMBL22543467 0.86 KLK7 (0.46) MMP2FKBP1AKMT2A
SCHEMBL22543395 0.86 KLK7 (0.46) MMP2FKBP1AKMT2A
Hydrochloric Acid SCHEMBL16611804 0.86 FKBP1A (0.41) MMP2FKBP1AALDH1A1CYP3A4TSHR
SCHEMBL22608698 0.85 FKBP1A (0.43) FKBP1A
SCHEMBL31294399 0.83 MMP2 (0.54) MMP2FKBP1AANPEPACEKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3854786-B1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES UBE CORP (JP) 2026-02-18 EP disclosed
US-12281074-B2 Method for producing amino acid derivatives UBE CORPORATION (JP) 2025-04-22 US disclosed
US-12202800-B2 Method for producing amino acid derivatives API CORPORATION (JP) 2025-01-21 US disclosed
US-20240150292-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES API CORPORATION (JP) 2024-05-09 US disclosed
US-11897844-B2 Method for producing amino acid derivatives API CORPORATION (JP) 2024-02-13 US disclosed
US-20240002340-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES API CORPORATION (JP) 2024-01-04 US disclosed
CN-112930338-A Process for the preparation of amino acid derivatives 株式会社API 2021-06-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150292-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES PTGS2, PTGES, PTGS1 MMP2 3356/4885FKBP1A 2960/4885ANPEP 500/4885
US-12202800-B2 Method for producing amino acid derivatives GLO1, BCAT2, BCAT1 MMP2 2853/4885FKBP1A 1159/4885ANPEP 144/4885
US-20240002340-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES GLO1, BCAT2, BCAT1 MMP2 2853/4885FKBP1A 1159/4885ANPEP 144/4885
US-11897844-B2 Method for producing amino acid derivatives PTGS2, PTGES, PTGES2 MMP2 3155/4885FKBP1A 3004/4885ANPEP 524/4885
US-12281074-B2 Method for producing amino acid derivatives PTGS2, PTGES, PTGES2 MMP2 3155/4885FKBP1A 3004/4885ANPEP 524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.