Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858182 | 0.94 | P2RX7 (0.44) | POLBP2RX7ALDH1A1LMNANPC1 | |
| SCHEMBL2854269 | 0.84 | RAB9A (0.46) | POLBP2RX7ALDH1A1GAALMNA | |
| SCHEMBL2852361 | 0.83 | KDM4E (0.47) | POLBP2RX7ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2860986 | 0.83 | MAPT (0.45) | POLBALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2854516 | 0.83 | P2RX7 (0.46) | POLBP2RX7ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2850871 | 0.82 | NPC1 (0.51) | POLBALDH1A1GAALMNAHTT | |
| SCHEMBL2852121 | 0.82 | P2RX7 (0.43) | P2RX7SMN1; SMN2RAB9AMAPTNPSR1 | |
| SCHEMBL2852799 | 0.81 | ALDH1A1 (0.46) | P2RX7ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2853182 | 0.81 | MAPT (0.42) | POLBP2RX7ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2848541 | 0.81 | RAB9A (0.43) | POLBP2RX7ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |