Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627421 | 0.92 | L3MBTL1 (0.54) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28622598 | 0.87 | MAPT (0.48) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28634881 | 0.86 | GAA (0.48) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL28619373 | 0.85 | MAPT (0.52) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28620396 | 0.85 | LMNA (0.48) | KDM4EHPGDMAPTLMNAHTT | |
| SCHEMBL28620716 | 0.83 | MAPT (0.45) | KDM4EALDH1A1MAPTLMNAHTT | |
| SCHEMBL28616300 | 0.83 | GPR183 (0.51) | ALDH1A1HPGDLMNATP53SMN1; SMN2 | |
| SCHEMBL28620401 | 0.83 | GPR183 (0.55) | ALDH1A1KMT2AMAPTLMNANPC1 | |
| SCHEMBL28615982 | 0.83 | MAPT (0.52) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28620945 | 0.81 | GPR183 (0.50) | KDM4EMAPTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440440-B | Naphthalene ring-containing 1,2, 4-oxadiazole-cinnamoyl piperazine compound and preparation method and application thereof | 贵州医科大学 | 2021-07-13 | — | — | CN | disclosed |