Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28622598 | 0.93 | MAPT (0.48) | L3MBTL1KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL28616298 | 0.92 | KDM4E (0.51) | KDM4EKMT2AALDH1A1MAPTTHRB | |
| SCHEMBL29165586 | 0.89 | MAPT (0.62) | L3MBTL1KDM4EKMT2AALDH1A1TDP1 | |
| SCHEMBL28620396 | 0.87 | LMNA (0.48) | KDM4EMAPTTHRBLMNANPC1 | |
| SCHEMBL28634881 | 0.87 | GAA (0.48) | L3MBTL1KMT2AMAPTMEN1LMNA | |
| SCHEMBL28619373 | 0.86 | MAPT (0.52) | KDM4EKMT2AALDH1A1TDP1MAPT | |
| SCHEMBL28620945 | 0.86 | GPR183 (0.50) | L3MBTL1KDM4ETDP1MAPTGAA | |
| SCHEMBL28620716 | 0.86 | MAPT (0.45) | L3MBTL1KDM4EALDH1A1MAPTTHRB | |
| SCHEMBL28620401 | 0.85 | GPR183 (0.55) | KMT2AALDH1A1MAPTTHRBLMNA | |
| SCHEMBL28616300 | 0.85 | GPR183 (0.51) | ALDH1A1LMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440440-B | Naphthalene ring-containing 1,2, 4-oxadiazole-cinnamoyl piperazine compound and preparation method and application thereof | 贵州医科大学 | 2021-07-13 | — | — | CN | disclosed |