Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627421 | 0.93 | L3MBTL1 (0.54) | MAPTLMNATHRBL3MBTL1ACHE | |
| SCHEMBL28616298 | 0.87 | KDM4E (0.51) | MAPTLMNATHRBTP53ACHE | |
| SCHEMBL28620401 | 0.86 | GPR183 (0.55) | MAPTLMNATHRBTP53KMT2A | |
| SCHEMBL28617767 | 0.85 | L3MBTL1 (0.55) | MAPTLMNATHRBTP53L3MBTL1 | |
| SCHEMBL28620396 | 0.84 | LMNA (0.48) | MAPTLMNATHRBTP53KDM4E | |
| SCHEMBL28634881 | 0.84 | GAA (0.48) | MAPTLMNATP53L3MBTL1KMT2A | |
| SCHEMBL28619373 | 0.83 | MAPT (0.52) | MAPTLMNATHRBTP53KDM4E | |
| SCHEMBL28620945 | 0.83 | GPR183 (0.50) | MAPTL3MBTL1KDM4ENPC1GAA | |
| SCHEMBL28616300 | 0.83 | GPR183 (0.51) | LMNATP53ALDH1A1 | |
| SCHEMBL28617647 | 0.83 | CCNC (0.48) | MAPTLMNATHRBTP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440440-B | Naphthalene ring-containing 1,2, 4-oxadiazole-cinnamoyl piperazine compound and preparation method and application thereof | 贵州医科大学 | 2021-07-13 | — | — | CN | disclosed |