Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GPR6 | P46095 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.34 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.34 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850809 | 0.84 | MAPT (0.43) | MAPTKMT2ANPSR1SMN1; SMN2RAB9A | |
| SCHEMBL2854533 | 0.84 | MEN1 (0.46) | MAPTGPR6ACHEP2RX7MEN1 | |
| SCHEMBL2852244 | 0.81 | MAPT (0.48) | MAPTGPR6ACHEMEN1KMT2A | |
| SCHEMBL2852552 | 0.80 | MEN1 (0.51) | MAPTGPR6ACHEP2RX7MEN1 | |
| SCHEMBL2856901 | 0.80 | MAPT (0.40) | MAPTGPR6ACHEP2RX7MEN1 | |
| SCHEMBL2860522 | 0.80 | MAPT (0.48) | MAPTMEN1KMT2ANPSR1NPC1 | |
| SCHEMBL2853465 | 0.80 | RAB9A (0.44) | L3MBTL1MAPTGPR6ACHENPSR1 | |
| SCHEMBL2857582 | 0.80 | MAPT (0.42) | MAPTGPR6ACHEP2RX7MEN1 | |
| SCHEMBL2858182 | 0.80 | P2RX7 (0.44) | MAPTP2RX7NPSR1NPC1RAB9A | |
| SCHEMBL2852353 | 0.80 | RAB9A (0.44) | MAPTGPR6ACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |