Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733386 | 0.82 | HSD17B10 (0.59) | HPGDHSD17B10ALOX15ALDH1A1KMT2A | |
| SCHEMBL4342445 | 0.80 | ALDH1A1 (0.50) | PTGS2HPGDHSD17B10ALOX15ALDH1A1 | |
| SCHEMBL28626078 | 0.80 | PTK2B (0.57) | HPGDHSD17B10ALOX15ALDH1A1KMT2A | |
| SCHEMBL733572 | 0.75 | MAPT (0.57) | HPGDALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL4325622 | 0.75 | PTGS2 (0.73) | PTGS2HPGDHSD17B10ALDH1A1KMT2A | |
| SCHEMBL7616356 | 0.74 | CES2 (0.59) | HSD17B10ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL8983809 | 0.71 | CES2 (0.59) | HPGDALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL5087773 | 0.71 | HSD17B10 (0.57) | HPGDHSD17B10ALOX15ALDH1A1KMT2A | |
| SCHEMBL70411 | 0.71 | HSD17B10 (0.61) | HPGDHSD17B10ALOX15ALDH1A1KMT2A | |
| SCHEMBL70410 | 0.71 | HSD17B10 (0.61) | HPGDHSD17B10ALOX15ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113444099-B | Reaction type hydrogen sulfide fluorescent probe and preparation and application thereof | 浙江大学城市学院 | 2022-06-21 | — | — | CN | disclosed |
| CN-113444099-A | Reaction type hydrogen sulfide fluorescent probe and preparation and application thereof | 浙江大学城市学院 | 2021-09-28 | — | — | CN | disclosed |