Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307175 | 0.91 | MEN1 (0.57) | TRPA1MEN1KMT2AHPGDCYP3A4 | |
| SCHEMBL13899836 | 0.90 | TRPA1 (0.50) | TRPA1MAPTMEN1KMT2AHPGD | |
| SCHEMBL14283807 | 0.87 | KEAP1 (0.46) | TRPA1MAPTMEN1KMT2AHPGD | |
| SCHEMBL5855849 | 0.81 | HSPA5 (0.57) | TRPA1MAPTMEN1KMT2AHPGD | |
| SCHEMBL30101971 | 0.80 | TRPA1 (0.48) | TRPA1CYP3A4HIF1AGABRA1GABRB2 | |
| SCHEMBL685704 | 0.80 | TRPA1 (0.48) | TRPA1CYP3A4HIF1AGABRA1GABRB2 | |
| SCHEMBL685611 | 0.78 | TRPA1 (0.52) | TRPA1GABRA1GABRB2ALDH1A1AKR1B1 | |
| SCHEMBL15524685 | 0.78 | TRPA1 (0.47) | TRPA1MAPTMEN1KMT2AHPGD | |
| SCHEMBL4613626 | 0.78 | GABRA1 (0.66) | TRPA1MAPTMEN1KMT2AHPGD | |
| SCHEMBL14760945 | 0.78 | TRPA1 (0.47) | TRPA1MAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354666-A | Four kinds of D-A' - (Pi-A)2Type polymeric salicylaldehyde Schiff base derivative metal complex and preparation method and application thereof | 湘潭大学 | 2021-09-07 | — | — | CN | claimed |
| CN-112250843-B | Four kinds of D-A' - (pi-A) 2 Polymeric alkylated salicylaldehyde Schiff base derivative metal complex and preparation method and application thereof | 湘潭大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-113354666-B | Four kinds of D-A' - (pi-A) 2 Metal complex of polymeric salicylaldehyde Schiff base derivative, preparation method and application thereof | 湘潭大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-113354666-A | Four kinds of D-A' - (Pi-A)2Type polymeric salicylaldehyde Schiff base derivative metal complex and preparation method and application thereof | 湘潭大学 | 2021-09-07 | — | — | CN | disclosed |
| CN-112250843-A | Four kinds of D-A' - (Pi-A)2Type polymerized alkylated salicylaldehyde Schiff base derivative metal complex and preparation method and application thereof | 湘潭大学 | 2021-01-22 | — | — | CN | disclosed |