Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 6/20 | 0.45 |
| ▸ | CA2 | P00918 | 6/20 | 0.45 |
| ▸ | CA12 | O43570 | 5/20 | 0.45 |
| ▸ | CA9 | Q16790 | 5/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.45 |
| ▸ | CA3 | P07451 | 3/20 | 0.45 |
| ▸ | CA4 | P22748 | 3/20 | 0.45 |
| ▸ | CA6 | P23280 | 3/20 | 0.45 |
| ▸ | CA5A | P35218 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2863852 | 0.80 | ALDH1A1 (0.43) | KMT2APOLBCA1CA2CA12 | |
| SCHEMBL6931644 | 0.78 | CA2 (0.50) | KMT2APOLBCA1CA2CA12 | |
| SCHEMBL30724830 | 0.78 | MAPK1 (0.57) | KMT2APOLBMAPK1CA1CA2 | |
| SCHEMBL2860305 | 0.76 | PKM (0.47) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL31757009 | 0.76 | ALDH1A1 (0.44) | KMT2ACA1CA2MEN1ALDH1A1 | |
| SCHEMBL7724566 | 0.75 | MAPT (0.57) | KMT2APOLBCA2MEN1ALDH1A1 | |
| SCHEMBL7691211 | 0.75 | MMP2 (0.45) | KMT2APOLBCA2CA12MMP2 | |
| SCHEMBL7696538 | 0.74 | MMP2 (0.41) | KMT2APOLBCA1CA2CA9 | |
| SCHEMBL29447197 | 0.72 | CA2 (0.55) | KMT2APOLBCA1CA2CA12 | |
| SCHEMBL11973333 | 0.72 | FLT1 (0.50) | KMT2ACA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100174104-A1 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION WITH DIAZOSULFONES | UNIVERSITY OF SOUTH FLORIDA | 2010-07-08 | — | — | US | disclosed |
| US-20100174104-A1 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION WITH DIAZOSULFONES | UNIVERSITY OF SOUTH FLORIDA | 2010-07-08 | — | — | US | disclosed |
| WO-2009114849-A1 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION WITH DIAZOSULFONES | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174104-A1 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION WITH DIAZOSULFONES | CYCS, TST, CBS | KMT2A 1568/4885POLB 3606/4885MAPK1 4253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.