Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1089447 | 0.86 | ALDH1A1 (0.43) | ALDH1A1GAACA1CA2MMP1 | |
| SCHEMBL9010795 | 0.83 | CES2 (0.48) | ALDH1A1GAALMNAPOLBKMT2A | |
| SCHEMBL384657 | 0.81 | ALDH1A1 (0.44) | ALDH1A1GAAPKMCA1CA2 | |
| SCHEMBL31757009 | 0.81 | ALDH1A1 (0.44) | ALDH1A1GAACA1CA2LMNA | |
| SCHEMBL563251 | 0.81 | ALDH1A1 (0.40) | ALDH1A1GAACA1CA2MMP1 | |
| SCHEMBL2860305 | 0.81 | PKM (0.47) | GAAPKMCA1CA2MMP1 | |
| SCHEMBL7724566 | 0.80 | MAPT (0.57) | ALDH1A1GAAPKMCA2CYP3A4 | |
| SCHEMBL2865337 | 0.80 | KMT2A (0.47) | ALDH1A1PKMCA1CA2MMP1 | |
| SCHEMBL384364 | 0.79 | CES2 (0.51) | ALDH1A1CYP3A4LMNAKMT2AHTT | |
| SCHEMBL7696538 | 0.79 | MMP2 (0.41) | ALDH1A1GAAPKMCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100174104-A1 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION WITH DIAZOSULFONES | UNIVERSITY OF SOUTH FLORIDA | 2010-07-08 | — | — | US | disclosed |
| US-20100174104-A1 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION WITH DIAZOSULFONES | UNIVERSITY OF SOUTH FLORIDA | 2010-07-08 | — | — | US | disclosed |
| WO-2009114849-A1 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION WITH DIAZOSULFONES | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174104-A1 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION WITH DIAZOSULFONES | CYCS, TST, CBS | ALDH1A1 818/4885GAA 4661/4885PKM 3682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.