SCHEMBL2865883

SCHEMBL2865883

Cl[Si](Cl)(Cl)CCc1ccc(-c2c3ccccc3c(-c3ccccc3)c3c(-c4ccccc4)c4ccccc4c(-c4ccccc4)c23)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.36
HIF1A Q16665 3/20 0.35
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
MMP12 P39900 1/20 0.34
MMP13 P45452 1/20 0.34
MMP14 P50281 1/20 0.34
KDM4E B2RXH2 2/20 0.33
MAPT P10636 2/20 0.33
TAAR1 Q96RJ0 1/20 0.33
HSD11B1 P28845 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
FDFT1 P37268 1/20 0.33
KCNH2 Q12809 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2864709 0.93 FFAR1 (0.38) FFAR1HIF1AMMP12KDM4EMAPT
SCHEMBL2867796 0.90 TP53 (0.35) FFAR1HIF1AKDM4EHSD11B1MEN1
SCHEMBL5493502 0.84 FFAR1 (0.48) FFAR1HIF1AMMP2MMP9MMP12
SCHEMBL2861031 0.83 MAOB (0.39) FFAR1HIF1AMMP12TAAR1HSD11B1
SCHEMBL2867556 0.79 MAOB (0.41) FFAR1HIF1AALDH1A1LMNACYP1A2
SCHEMBL2865943 0.79 ALOX5 (0.44) L3MBTL1
SCHEMBL208903 0.75 TDP1 (0.52) TAAR1KCNH2ALDH1A1LMNACYP1A2
SCHEMBL6532094 0.73 TDP1 (0.50) TAAR1KCNH2ALDH1A1LMNACYP1A2
SCHEMBL282856 0.73 ALDH1A1 (0.50) KDM4EMAPTTAAR1ALDH1A1LMNA
SCHEMBL29362903 0.73 ALDH1A1 (0.50) KDM4EMAPTTAAR1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7749921-B2 Semiconductor element, method for manufacturing the semiconductor element, electronic device and method for manufacturing the electronic device PANASONIC CORPORATION (JP) 2010-07-06 US disclosed
US-20090194763-A1 SEMICONDUCTOR ELEMENT, METHOD FOR MANUFACTURING THE SEMICONDUCTOR ELEMENT, ELECTRONIC DEVICE AND METHOD FOR MANUFACTURING THE ELECTRONIC DEVICE PANASONIC CORPORATION (JP) 2009-08-06 US disclosed