SCHEMBL2867556

SCHEMBL2867556

Cl[Si](Cl)(Cl)CCc1ccc(-c2ccc(-c3ccc(CC[Si](Cl)(Cl)Cl)cc3)c3ccccc23)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.41
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
TNF P01375 1/20 0.34
CSNK2A1 P68400 2/20 0.33
HIF1A Q16665 2/20 0.33
HTT P42858 1/20 0.33
CNR2 P34972 1/20 0.33
FFAR1 O14842 1/20 0.32
NPC1 O15118 1/20 0.32
KDM1A O60341 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
CYP2C8 P10632 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2861031 0.96 MAOB (0.39) MAOBRXRARXRBTDP1CSNK2A1
SCHEMBL2867796 0.85 TP53 (0.35) MAOBTDP1HIF1AHTTFFAR1
SCHEMBL5493502 0.82 FFAR1 (0.48) HIF1AHTTCNR2FFAR1LMNA
SCHEMBL2864709 0.81 FFAR1 (0.38) TDP1HIF1ACNR2FFAR1
SCHEMBL6848455 0.78 CA2 (0.38) MAOBTDP1ALDH1A1CYP1A2HTR1A
SCHEMBL2865943 0.78 ALOX5 (0.44)
SCHEMBL208903 0.77 TDP1 (0.52) MAOBTDP1NPC1KDM1AALDH1A1
SCHEMBL6532094 0.74 TDP1 (0.50) MAOBTDP1NPC1KDM1AALDH1A1
SCHEMBL5483434 0.71 FFAR1 (0.46) MAOBHIF1AFFAR1
SCHEMBL5490774 0.70 TAAR1 (0.52) MAOBLMNACYP1A2CYP2D6IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7749921-B2 Semiconductor element, method for manufacturing the semiconductor element, electronic device and method for manufacturing the electronic device PANASONIC CORPORATION (JP) 2010-07-06 US disclosed
US-20090194763-A1 SEMICONDUCTOR ELEMENT, METHOD FOR MANUFACTURING THE SEMICONDUCTOR ELEMENT, ELECTRONIC DEVICE AND METHOD FOR MANUFACTURING THE ELECTRONIC DEVICE PANASONIC CORPORATION (JP) 2009-08-06 US disclosed