Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL28670856

O=S(=O)([O-])C(F)(F)F.[KH].[Na+]

nearest known ligand 0.41

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Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Trifluoromethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 2/20 0.41
CA2 known ✓ P00918 2/20 0.41
CA7 P43166 1/20 0.41
CA13 Q8N1Q1 1/20 0.41
GPR3 P46089 2/20 0.41
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 1/20 0.38
ACHE P22303 2/20 0.32
PTPN1 P18031 1/20 0.31
KCNH2 Q12809 6/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL19915225 0.96 CA1 (0.44) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL158641 0.96
Trifluoromethanesulfonic Acid SCHEMBL25301943 0.96 CA1 (0.44) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL796767 0.92 CA1 (0.41) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL28993864 0.92 CA1 (0.41) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL28741583 0.92 CA1 (0.41) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL29808804 0.89 GPR3 (0.39) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL25285896 0.88 CA1 (0.44) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL25255863 0.88 CA1 (0.44) CA1CA2CA7CA13GPR3
Trifluoromethanesulfonic Acid SCHEMBL25292546 0.88 GPR3 (0.48) CA1CA2CA7CA13GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109817912-B Sodium/potassium ion battery negative electrode material and preparation method and application thereof 暨南大学 2021-07-27 CN disclosed