Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28022391 | 0.88 | PTGS2 (0.38) | ACLYPTGS1PTGS2KIF11 | |
| SCHEMBL28022942 | 0.72 | CA2 (0.40) | PTGES2PTGS2KIF11 | |
| SCHEMBL28022345 | 0.70 | PTGS2 (0.44) | PTGS1PTGS2KIF11 | |
| SCHEMBL173606 | 0.68 | SCN9A (0.38) | ACLYAVPR2GPR27 | |
| Trifluoroacetic Acid SCHEMBL28022384 | 0.67 | FABP4 (0.38) | PTGS2 | |
| SCHEMBL28536731 | 0.66 | ACLY (0.35) | ACLYRORC | |
| SCHEMBL1069088 | 0.65 | CA12 (0.49) | RORCPTGS1PTGS2 | |
| SCHEMBL14744335 | 0.64 | GRIA1 (0.39) | ACLYRORC | |
| SCHEMBL6917671 | 0.64 | FABP4 (0.44) | PTGES2 | |
| SCHEMBL2452806 | 0.64 | CA1 (0.41) | PTGES2PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102449-A | Antiviral compounds | HOFFMANN LA ROCHE | 2015-11-25 | — | — | CN | disclosed |