Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27743313 | 0.81 | ALOX5 (0.48) | ALOX5ADRB1MAPTKMT2ACYP1A2 | |
| SCHEMBL28103502 | 0.80 | ALOX5 (0.47) | ALOX5MAPTMGLLKMT2AMEN1 | |
| SCHEMBL27873897 | 0.80 | ALOX5 (0.47) | ALOX5NPC1MGLLKMT2AMEN1 | |
| SCHEMBL27671224 | 0.79 | ALOX5 (0.41) | ALOX5ADRB1NPC1KMT2AMEN1 | |
| SCHEMBL28103275 | 0.77 | PRMT6 (0.37) | ALOX5 | |
| SCHEMBL27873899 | 0.76 | SLC6A2 (0.38) | ALOX5MGLLDRD2 | |
| SCHEMBL28103298 | 0.73 | DRD2 (0.48) | ADRB1MAPTMGLLKMT2AMEN1 | |
| SCHEMBL28158046 | 0.73 | FFAR4 (0.34) | ALOX5ADRB1FFAR4KMT2ATSHR | |
| SCHEMBL28039321 | 0.72 | ADRB1 (0.45) | ADRB1MAPTKCNH2 | |
| SCHEMBL27380663 | 0.70 | ALOX5 (0.44) | ALOX5ADRB1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061950-A | Method for producing pyrazole compound | 住友化学株式会社 | 2016-10-26 | — | — | CN | disclosed |