SCHEMBL28876309

SCHEMBL28876309

Cc1ccc(OP(Oc2ccc(C)cc2)c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.42
ACHE P22303 3/20 0.42
TSHR P16473 2/20 0.42
ALOX12 P18054 1/20 0.42
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
DRD2 P14416 2/20 0.38
DRD4 P21917 2/20 0.38
DRD3 P35462 2/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HPGD P15428 1/20 0.37
PPARG P37231 1/20 0.36
CYP3A4 P08684 2/20 0.35
TEAD4 Q15561 1/20 0.35
MAPT P10636 2/20 0.35
TDP1 Q9NUW8 3/20 0.35
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1727101 0.89 ACHE (0.46) LMNAACHETSHRDRD2DRD4
SCHEMBL11078704 0.87 LMNA (0.42) LMNAACHETSHRALOX12HTT
SCHEMBL8939016 0.85 DRD2 (0.36) LMNAACHETSHRALOX12HTT
SCHEMBL195903 0.84 LTA4H (0.43) TSHRKMT2ACYP3A4TDP1ALDH1A1
SCHEMBL13914845 0.81 LMNA (0.40) LMNAACHETSHRALOX12HTT
SCHEMBL444404 0.79 HTT (0.48) LMNAACHETSHRALOX12HTT
SCHEMBL446426 0.79 HTT (0.48) LMNAACHETSHRALOX12HTT
SCHEMBL24796098 0.78 NFE2L2 (0.37) LMNAHTTMEN1KMT2AHPGD
SCHEMBL14060796 0.78 ESR1 (0.52) LMNADRD2DRD4DRD3MEN1
SCHEMBL29286665 0.78 ACHE (0.50) LMNAACHETSHRALOX12HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109721508-B Method for preparing 3-pentenenitrile 安徽省安庆市曙光化工股份有限公司 2022-10-04 CN claimed
CN-109651195-B Method for producing 3-pentenenitrile through isomerization reaction of 2-pentenenitrile 安徽省安庆市曙光化工股份有限公司 2021-08-24 CN claimed
CN-110194843-B Phosphorus-containing phenoxy resin, resin composition, material for circuit board, and cured product 日铁化学材料株式会社 2023-01-03 CN disclosed
CN-109721508-B Method for preparing 3-pentenenitrile 安徽省安庆市曙光化工股份有限公司 2022-10-04 CN disclosed
CN-109651195-B Method for producing 3-pentenenitrile through isomerization reaction of 2-pentenenitrile 安徽省安庆市曙光化工股份有限公司 2021-08-24 CN disclosed