Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.37 |
| ▸ | GAK | O14976 | 2/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.35 |
| ▸ | COQ8A | Q8NI60 | 2/20 | 0.35 |
| ▸ | NLK | Q9UBE8 | 2/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28338774 | 0.85 | PTGS2 (0.35) | PTGS2PTK2GAKRIPK2COQ8A | |
| SCHEMBL28168774 | 0.84 | PTK6 (0.41) | MEN1LMNAKMT2AMAPK14EGFR | |
| SCHEMBL28678155 | 0.79 | HTR2A (0.45) | MEN1KMT2A | |
| SCHEMBL27908784 | 0.76 | MTNR1A (0.43) | PTK2BRAFLMNAABL1EGFR | |
| SCHEMBL28293160 | 0.74 | L3MBTL1 (0.40) | JAK2 | |
| SCHEMBL28844707 | 0.74 | IDO1 (0.38) | EGFRIDO1TDO2 | |
| SCHEMBL27369292 | 0.72 | GPR84 (0.44) | MEN1KMT2A | |
| SCHEMBL27908791 | 0.71 | HTR2A (0.35) | MEN1KMT2A | |
| SCHEMBL27906752 | 0.71 | FFAR1 (0.43) | — | |
| SCHEMBL27771264 | 0.71 | HTR2A (0.44) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-A | Benzazole compounds and preparation method thereof, pharmaceutical composition and purposes | INST MATERIA MEDICA CAMS | 2019-11-22 | — | — | CN | disclosed |