SCHEMBL3043213

SCHEMBL3043213

O=C(O)CCON1C(=O)CCC1=O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.38
KMT2A Q03164 1/20 0.37
ATM Q13315 1/20 0.37
MAPK1 P28482 1/20 0.36
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.36
LMNA P02545 3/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.33
FGF2 P09038 1/20 0.33
ALDH1A1 P00352 2/20 0.33
PKM P14618 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
PARL Q9H300 1/20 0.32
ALKBH5 Q6P6C2 1/20 0.32
SUCNR1 Q9BXA5 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
PPM1B O75688 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28511791 0.88 ALOX12 (0.53) ALOX12SMN1; SMN2KMT2AMAPK1KDM4E
SCHEMBL8652116 0.86 ALOX12 (0.56) ALOX12SMN1; SMN2KMT2AKDM4EPOLB
SCHEMBL16290005 0.79 ALOX12 (0.53) ALOX12SMN1; SMN2MAPK1KDM4EPOLB
SCHEMBL28933285 0.78 ALOX12 (0.42) ALOX12SMN1; SMN2KMT2AATMMAPK1
SCHEMBL27664746 0.76 ALOX12 (0.45) ALOX12SMN1; SMN2MAPK1KDM4EPOLB
SCHEMBL17701607 0.76 KMT2A (0.33) ALOX12KMT2AATM
SCHEMBL5246024 0.76 ALOX12 (0.47) ALOX12SMN1; SMN2KMT2AMAPK1KDM4E
SCHEMBL20786977 0.75 ALOX12 (0.43) ALOX12SMN1; SMN2MAPK1KDM4EPOLB
SCHEMBL24507865 0.74 KMT2A (0.33) ALOX12KMT2AATM
SCHEMBL19544549 0.74 KMT2A (0.33) ALOX12KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747283-A1 TYROSINE-PROTEIN KINASE MEMBRANE RECEPTOR 1 (ROR1) ANTIBODY-DRUG CONJUGATES AND USES THEREOF Exelixis, Inc. (US) 2026-05-27 EP disclosed
EP-4746922-A2 INTERLEUKIN-13 RECEPTOR SUBUNIT ALPHA-2 ANTIBODY-DRUG CONJUGATES AND USES THEREOF Exelixis, Inc. (US) 2026-05-27 EP disclosed
EP-4747282-A1 ACTIVATABLE TYROSINE-PROTEIN KINASE MEMBRANE RECEPTOR (ROR) ANTIBODY-DRUG CONJUGATES AND USES THEREOF Exelixis, Inc. (US) 2026-05-27 EP disclosed
US-20260083856-A1 THIAZOLIDINE LINKERS FOR PROTEIN-DRUG CONJUGATES AND USES THEREOF SCHERER TECHNOLOGIES LLC R P (US) 2026-03-26 US disclosed
US-20250381290-A1 Antibody Conjugates and Methods of Making and Using the Same SCHERER TECHNOLOGIES LLC R P (US) 2025-12-18 US disclosed
US-20250262315-A1 TRIPEPTIDE LINKERS AND METHODS OF USE THEREOF THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2025-08-21 US disclosed
EP-4592275-A2 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE Redwood Bioscience, Inc. (US) 2025-07-30 EP disclosed
EP-4583922-A2 TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND USES THEREOF Exelixis, Inc. (US) 2025-07-16 EP disclosed
WO-2025064424-A9 TANDEM-CLEAVAGE LINKERS FOR ANTIBODY-DRUG CONJUGATES AND USES THEREOF R.P. SCHERER TECHNOLOGIES, LLC (US) 2025-06-19 WO disclosed
US-20250179117-A1 GLYCOSIDE DUAL-CLEAVAGE LINKERS FOR ANTIBODY-DRUG CONJUGATES ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2025-06-05 US disclosed
US-20150157736-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE R.P. SCHERER TECHNOLOGIES, LLC 2015-06-11 US disclosed
WO-2015081282-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE, INC. (US) 2015-06-04 WO disclosed
WO-2014078566-A1 HYDRAZINYL-INDOLE COMPOUNDS AND CONJUGATES REDWOOD BIOSCIENCE, INC. (US) 2014-05-22 WO disclosed
US-20140141025-A1 HYDRAZINYL-INDOLE COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE, INC. (US) 2014-05-22 US disclosed
WO-2014074218-A1 COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE, INC. (US) 2014-05-15 WO disclosed
EP-2663647-A2 ALDEHYDE-TAGGED IMMUNOGLOBULIN POLYPEPTIDES AND METHOD OF USE THEREOF Redwood Bioscience, Inc. (US) 2013-11-20 EP disclosed
US-20120183566-A1 Aldehyde-Tagged Immunoglobulin Polypeptides and Methods of Use Thereof REDWOOD BIOSCIENCE, INC. 2012-07-19 US disclosed
WO-2012097333-A2 ALDEHYDE-TAGGED IMMUNOGLOBULIN POLYPEPTIDES AND METHOD OF USE THEREOF REDWOOD BIOSCIENCE, INC. (US) 2012-07-19 WO disclosed
WO-2010096394-A2 ALDEHYDE-TAGGED PROTEIN-BASED DRUG CARRIERS AND METHODS OF USE REDWOOD BIOSCIENCES, INC. (US) 2010-08-26 WO disclosed
US-20100210543-A1 Aldehyde-Tagged Protein-Based Drug Carriers and Methods of Use REDWOOD BIOSCIENCE, INC. 2010-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210543-A1 Aldehyde-Tagged Protein-Based Drug Carriers and Methods of Use ALDH3A1, ALDH1A1, ALDH2 ALOX12 4139/4885SMN1; SMN2 2725/4885KMT2A 3332/4885
US-20150157736-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE DNPEP, QPCT, PDS5A ALOX12 3166/4885SMN1; SMN2 3732/4885KMT2A 1630/4885
US-20250179117-A1 GLYCOSIDE DUAL-CLEAVAGE LINKERS FOR ANTIBODY-DRUG CONJUGATES ENGASE, FUT5, FUT6 ALOX12 2858/4885SMN1; SMN2 3586/4885KMT2A 1153/4885
US-20120183566-A1 Aldehyde-Tagged Immunoglobulin Polypeptides and Methods of Use Thereof IGSF11, PFAS, FGB ALOX12 2339/4885SMN1; SMN2 4763/4885KMT2A 2396/4885
US-20140141025-A1 HYDRAZINYL-INDOLE COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE HNMT, AANAT, INMT ALOX12 4086/4885SMN1; SMN2 4058/4885KMT2A 1677/4885
US-20250381290-A1 Antibody Conjugates and Methods of Making and Using the Same PFAS, FGR, FGB ALOX12 3603/4885SMN1; SMN2 4677/4885KMT2A 2004/4885
US-20250262315-A1 TRIPEPTIDE LINKERS AND METHODS OF USE THEREOF DNPEP, VIP, LNPEP ALOX12 4425/4885SMN1; SMN2 2524/4885KMT2A 3255/4885
US-20260083856-A1 THIAZOLIDINE LINKERS FOR PROTEIN-DRUG CONJUGATES AND USES THEREOF BRWD1, TMIGD3, TXNL1 ALOX12 4746/4885SMN1; SMN2 1114/4885KMT2A 923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.