SCHEMBL289718

SCHEMBL289718

COc1cccc(OBOc2cccc(OC)c2OC)c1OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.48
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
NFE2L2 Q16236 5/20 0.43
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL544086 0.86 SMN1; SMN2 (0.52) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL23440 0.86 AOC3 (0.40) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL25434306 0.85 CA1 (0.61) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL151213 0.85 CA1 (0.61) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL27753904 0.85 CA1 (0.61) SMN1; SMN2CA12CA1CA2CA4
Bromide SCHEMBL28158222 0.83 SMN1; SMN2 (0.58) SMN1; SMN2CA12CA1CA2CA4
Ammonia Solution, Strong SCHEMBL4268652 0.83 SMN1; SMN2 (0.58) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL27731704 0.83 SMN1; SMN2 (0.58) SMN1; SMN2CA12CA1CA2CA4
Hydrochloric Acid SCHEMBL31658961 0.83 SMN1; SMN2 (0.58) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL14120688 0.83 CA12 (0.37) SMN1; SMN2CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12402529-B2 Organic compound, composition, organic optoelectronic device, and display device SAMSUNG SDI CO., LTD. (KR) 2025-08-26 US disclosed
WO-2024122460-A1 RESIST COMPOSITION AND METHOD FOR PRODUCING SAME 株式会社日本触媒 2024-06-13 WO disclosed
US-11844271-B2 Organic compound, composition, organic optoelectronic device, and display apparatus SAMSUNG SDI CO., LTD. (KR) 2023-12-12 US disclosed
US-20230371371-A1 ORGANIC COMPOUND, COMPOSITION, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-11-16 US disclosed
US-20200388765-A1 ORGANIC COMPOUND, COMPOSITION, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY APPARATUS SAMSUNG SDI CO., LTD. (KR) 2020-12-10 US disclosed
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-04 US disclosed
US-10246422-B2 Heterocyclic compounds and use thereof in medicine and in cosmetics GALDERMA RESEARCH & DEVELOPMENT (FR) 2019-04-02 US disclosed
US-20180050992-A1 NOVEL HETEROCYCLIC COMPOUNDS AND USE THEREOF IN MEDICINE AND IN COSMETICS GALDERMA RESEARCH & DEVELOPMENT (FR) 2018-02-22 US disclosed
CN-107428744-A Novel heterocyclic compounds and its application in medicine and cosmetics 盖尔德马研究及发展公司 2017-12-01 CN disclosed
CN-104870445-B New dihydro-pyrimidin and isobioquin group and its pharmaceutical composition (GPR84 antagonists) for treating inflammatory disease 加拉帕戈斯股份有限公司 2017-09-15 CN disclosed
US-20060241172-A1 Benzodioxane and benzodioxolane derivatives and uses thereof WYETH (US) 2006-10-26 US disclosed
US-7119205-B2 Thienopyridones as AMPK activators for the treatment of diabetes and obesity ABBOTT LABORATORIES (US) 2006-10-10 US disclosed
US-20060100218-A1 Phosphodiesterase 4; asthma, chronic obstructive pulmonary disease, Alzheimer's disease, diffuse large-cell B cell lymphoma, and chronic lymphocytic leukemia; 8-[3-(3,4-dimethoxy-phenyl)-pyrrolo[2,3-b]pyridine-1-sulfonyl]-quinoline PLEXXIKON, INC. 2006-05-11 US disclosed
WO-2006026754-A9 BICYCLIC HETEROARYL PDE4B INHIBITORS PLEXXIKON INC (US) 2006-04-20 WO disclosed
WO-2006026754-A2 BICYCLIC HETEROARYL PDE4B INHIBITORS PLEXXIKON, INC. (US) 2006-03-09 WO disclosed
EP-1532113-A2 SUBSTITUTED HIHYDROQUINOLINES AS GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) 2005-05-25 EP disclosed
US-6858627-B2 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2005-02-22 US disclosed
US-20050038068-A1 Thienopyridones as AMPK activators for the treatment of diabetes and obesity ABBVIE INC. 2005-02-17 US disclosed
US-20040116455-A1 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 2004-06-17 US disclosed
WO-2004018429-A2 SUBSTITUTED HIHYDROQUINOLINES AS GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2004-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060100218-A1 Phosphodiesterase 4; asthma, chronic obstructive pulmonary disease, Alzheimer's disease, diffuse large-cell B cell lymphoma, and chronic lymphocytic leukemia; 8-[3-(3,4-dimethoxy-phenyl)-pyrrolo[2,3-b]pyridine-1-sulfonyl]-quinoline PDE4B, PDE4A, PDE4C SMN1; SMN2 3115/4885CA12 3109/4885CA1 383/4885
US-20230371371-A1 ORGANIC COMPOUND, COMPOSITION, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OCIAD1, OXER1, OR10J3 SMN1; SMN2 3621/4885CA12 573/4885CA1 1374/4885
US-20200388765-A1 ORGANIC COMPOUND, COMPOSITION, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY APPARATUS OCIAD1, OXER1, OR10J3 SMN1; SMN2 3529/4885CA12 739/4885CA1 1496/4885
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same CRY1, CRY2, CCNT1 SMN1; SMN2 4074/4885CA12 1240/4885CA1 1455/4885
US-20180050992-A1 NOVEL HETEROCYCLIC COMPOUNDS AND USE THEREOF IN MEDICINE AND IN COSMETICS MC1R, CALCRL, BDKRB2 SMN1; SMN2 4090/4885CA12 3904/4885CA1 4370/4885
US-20060241172-A1 Benzodioxane and benzodioxolane derivatives and uses thereof HTR2C, HTR1D, HTR1A SMN1; SMN2 1352/4885CA12 4780/4885CA1 4027/4885
US-20050038068-A1 Thienopyridones as AMPK activators for the treatment of diabetes and obesity PRKAG1, PRKAG3, PRKAG2 SMN1; SMN2 4596/4885CA12 4884/4885CA1 4878/4885
US-12402529-B2 Organic compound, composition, organic optoelectronic device, and display device OCIAD1, OXER1, OR10J3 SMN1; SMN2 3621/4885CA12 573/4885CA1 1374/4885
US-11844271-B2 Organic compound, composition, organic optoelectronic device, and display apparatus OCIAD1, OXER1, OR10J3 SMN1; SMN2 3529/4885CA12 739/4885CA1 1496/4885
US-10246422-B2 Heterocyclic compounds and use thereof in medicine and in cosmetics MC1R, BDKRB2, CCKBR SMN1; SMN2 3905/4885CA12 3779/4885CA1 4228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.