SCHEMBL544086

SCHEMBL544086

COc1cccc(OC)c1OBOc1c(OC)cccc1OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.52
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
CA7 P43166 3/20 0.50
CA9 Q16790 3/20 0.50
CA12 O43570 2/20 0.50
CA14 Q9ULX7 2/20 0.50
CA4 P22748 1/20 0.50
MAPK1 P28482 3/20 0.44
ALDH1A1 P00352 3/20 0.44
TP53 P04637 2/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
HSD17B10 Q99714 1/20 0.44
NFE2L2 Q16236 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL289718 0.86 SMN1; SMN2 (0.48) SMN1; SMN2CA1CA2CA7CA9
SCHEMBL1848425 0.85 KMT2A (0.45) SMN1; SMN2CA1CA2CA7CA9
SCHEMBL4621512 0.85 SMN1; SMN2 (0.44) SMN1; SMN2CA1CA2CA7CA9
SCHEMBL7227165 0.84 SMN1; SMN2 (0.42) SMN1; SMN2CA1CA2CA7CA9
SCHEMBL6501888 0.82 SMN1; SMN2 (0.41) SMN1; SMN2CA1CA2CA7CA9
SCHEMBL25962740 0.81 SMN1; SMN2 (0.48) SMN1; SMN2CA1CA2CA7CA9
SCHEMBL25434306 0.78 CA1 (0.61) SMN1; SMN2CA1CA2CA7CA9
SCHEMBL151213 0.78 CA1 (0.61) SMN1; SMN2CA1CA2CA7CA9
SCHEMBL27753904 0.78 CA1 (0.61) SMN1; SMN2CA1CA2CA7CA9
SCHEMBL23808 0.77 CA1 (0.68) SMN1; SMN2CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260150574-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DIODE, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2026-05-28 US disclosed
EP-4709724-A1 ANTICONVULSIVE COMPOUNDS AND USES THEREOF Jazz Pharmaceuticals Research UK Limited (GB) 2026-03-18 EP disclosed
US-12428429-B2 Amine compound and organic light-emitting diode including same SFC CO., LTD. (KR) 2025-09-30 US disclosed
US-12402529-B2 Organic compound, composition, organic optoelectronic device, and display device SAMSUNG SDI CO., LTD. (KR) 2025-08-26 US disclosed
US-20250002519-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME UNIV YALE (US) 2025-01-02 US disclosed
WO-2024236275-A1 ANTICONVULSIVE COMPOUNDS AND USES THEREOF JAZZ PHARMACEUTICALS RESEARCH UK LIMITED (GB) 2024-11-21 WO disclosed
US-12071445-B2 Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same YALE UNIVERSITY (US) 2024-08-27 US disclosed
EP-4389755-A1 FLUORESCENT COMPOUND AND FLUORESCENCE-LABELED BIOSUBSTANCE OBTAINED USING SAME FUJIFILM Corporation (JP) 2024-06-26 EP disclosed
US-20240110918-A1 FLUORESCENT COMPOUND AND FLUORESCENTLY LABELED BIOLOGICAL SUBSTANCE USING THE SAME FUJIFILM CORPORATION (JP) 2024-04-04 US disclosed
EP-3792989-B1 ORGANIC LIGHT EMITTING DIODE INCLUDING BORON COMPOUNDS SFC CO LTD (KR) 2024-03-06 EP disclosed
US-6403584-B1 CONJUNCTIVITIS, ALLERGIC RHINITIS, ALZHEIMER'S DISEASE, ASTHMA, ATHEROSCLEROSIS, AUTOLOGOUS BONE MARROW TRANSPLANTATION, ANTIINFLAMMATORY, ETC MERCK & CO., INC. 2002-06-11 US disclosed
EP-1203766-A2 Carboxylic acid derivatives that inhibit the binding of integrins to their receptors TEXAS BIOTECHNOLOGY CORPORATION (US) 2002-05-08 EP disclosed
EP-1196640-A2 ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES Applera Corporation (US) 2002-04-17 EP disclosed
US-20020037909-A1 Enamine derivatives UCB PHARMA S.A. (BE) 2002-03-28 US disclosed
WO-2001079173-A2 ENAMINE DERIVATIVES AS CELL ADHESION MOLECULES CELLTECH R & D LIMITED (GB) 2001-10-25 WO disclosed
US-20010020017-A1 Squaric acid derivatives CELLTECH R&D LIMITED (GB) 2001-09-06 US disclosed
WO-2001057264-A2 ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES APPLERA CORPORATION (US) 2001-08-09 WO disclosed
WO-2001047867-A1 SQUARIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS CELLTECH R & D LIMITED (GB) 2001-07-05 WO disclosed
US-6221604-B1 CONJUGATED TO SUBSTRATES SUCH AS NUCLEOSIDES OR NUCLEOTIDES AND USED AS DETECTION LABELS IN MOLECULAR BIOLOGY EXPERIMENTS; ENERGY TRANSFER DYE PE CORPORATION 2001-04-24 US disclosed
WO-2000071572-A1 SUBSTITUTED BETA-ALANINE DERIVATIVES AS CELL ADHESION INHIBITORS MERCK & CO., INC. (US) 2000-11-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002519-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME TIMCC, YAP1, TET2 SMN1; SMN2 2929/4885CA1 44/4885CA2 93/4885
US-20240110918-A1 FLUORESCENT COMPOUND AND FLUORESCENTLY LABELED BIOLOGICAL SUBSTANCE USING THE SAME F11, NPFFR1, FGF23 SMN1; SMN2 3176/4885CA1 485/4885CA2 476/4885
US-20020037909-A1 Enamine derivatives CCR1, ITGB2, CCR10 SMN1; SMN2 3892/4885CA1 4444/4885CA2 2933/4885
US-20010020017-A1 Squaric acid derivatives SUCNR1, HCAR1, CCR1 SMN1; SMN2 1016/4885CA1 2102/4885CA2 572/4885
US-12428429-B2 Amine compound and organic light-emitting diode including same MAOA, AOC2, MAOB SMN1; SMN2 586/4885CA1 4475/4885CA2 4780/4885
US-12402529-B2 Organic compound, composition, organic optoelectronic device, and display device OCIAD1, OXER1, OR10J3 SMN1; SMN2 3621/4885CA1 1374/4885CA2 1556/4885
US-12071445-B2 Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same TIMCC, YAP1, TET2 SMN1; SMN2 3274/4885CA1 44/4885CA2 108/4885
US-20260150574-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DIODE, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE OXER1, OR10J3, OPRD1 SMN1; SMN2 2663/4885CA1 2395/4885CA2 2350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.