SCHEMBL289956

SCHEMBL289956

CC(C)(C)OC(=O)NC1(C(=O)O)CCOCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GHSR Q92847 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
GAA P10253 2/20 0.35
MAPK1 P28482 1/20 0.35
CTSL P07711 2/20 0.35
CTSD P07339 1/20 0.35
CTSB P07858 1/20 0.35
CTSS P25774 1/20 0.35
HCRTR2 O43614 1/20 0.33
BTK Q06187 1/20 0.33
PRKDC P78527 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
RET P07949 1/20 0.32
CTSK P43235 1/20 0.32
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29203009 0.90 GAA (0.36) USP2SMN1; SMN2GHSRMEN1KMT2A
SCHEMBL2566097 0.90 GAA (0.36) USP2SMN1; SMN2GHSRMEN1KMT2A
SCHEMBL142219 0.88 MEN1 (0.39) GHSRMEN1KMT2AGAAMAPK1
SCHEMBL15116541 0.87 USP2 (0.38) USP2SMN1; SMN2GHSRMEN1KMT2A
SCHEMBL5128975 0.85 USP2 (0.37) USP2SMN1; SMN2GHSRMEN1KMT2A
SCHEMBL2745968 0.85 USP2 (0.37) USP2SMN1; SMN2GHSRMEN1KMT2A
SCHEMBL24071170 0.85 GAA (0.33) USP2SMN1; SMN2GHSRMEN1KMT2A
SCHEMBL76966 0.84 BTK (0.38) GHSRMEN1KMT2AGAAMAPK1
SCHEMBL202837 0.84 BTK (0.38) GHSRMEN1KMT2AGAAMAPK1
SCHEMBL29129539 0.84 MEN1 (0.36) USP2SMN1; SMN2MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116874803-A Antibacterial dendritic polyester polymer and preparation method and application thereof 清华大学深圳国际研究生院 2023-10-13 CN claimed
EP-4720058-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF Casma Therapeutics, Inc. (US) 2026-04-08 EP disclosed
US-12552804-B2 Tricyclic heterocycles as FGFR inhibitors INCYTE CORPORATION (US) 2026-02-17 US disclosed
US-20260028341-A1 IMIDAZOTRIAZINE DERIVATIVES AS IL-17 MODULATORS UCB Biopharma SRL (BE) 2026-01-29 US disclosed
US-12527779-B2 Prostaglandin E2 (PGE2) EP4 receptor antagonists DOMAIN THERAPEUTICS (FR) 2026-01-20 US disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 US disclosed
US-20250223291-A1 IMIDAZOTRIAZINES AND IMIDAZOPYRIMIDINES AS KINASE INHIBITORS INCYTE CORPORATION 2025-07-10 US disclosed
EP-4558223-A1 IMIDAZOTRIAZINE DERIVATIVES AS IL-17 MODULATORS UCB Biopharma SRL (BE) 2025-05-28 EP disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 EP disclosed
EP-1539686-A1 INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE WARNER-LAMBERT COMPANY LLC (US) 2005-06-15 EP disclosed
US-20050075356-A1 Dihydroxypyrimidine carboxamide inhibitors of hiv integrase ISTITUTO DI RICHERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) 2005-04-07 US disclosed
US-20040167131-A1 Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade PFIZER INC. 2004-08-26 US disclosed
EP-1441734-A1 DIHYDROXYPYRIMIDINE CARBOXAMIDE INHIBITORS OF HIV INTEGRASE Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) 2004-08-04 EP disclosed
US-6713580-B2 CYCLIZED AMINO ACIDS ARE COUPLED TO A POLYSTYRENE DERIVATIVE FOR USE IN SYNTHESIS OF PEPTIDES AND OF AMINO ACID CONTAINING COMPOUNDS FOR DRUG DISCOVERY PHARMACORE, INC. 2004-03-30 US disclosed
WO-2004024679-A1 INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE WARNER-LAMBERT COMPANY LLC (US) 2004-03-25 WO disclosed
EP-1373195-A2 QUATERNARY AMINO ACIDS ON SOLID SUPPORTS PharmaCore, Inc, (US) 2004-01-02 EP disclosed
WO-2003035076-A1 DIHYDROXYPYRIMIDINE CARBOXAMIDE INHIBITORS OF HIV INTEGRASE ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) 2003-05-01 WO disclosed
US-20020086949-A1 Cyclized amino acids are coupled to a polystyrene derivative for use in synthesis of peptides and of amino acid containing compounds for drug discovery PHARMACORE, INC. 2002-07-04 US disclosed
WO-2002046128-A2 QUATERNARY AMINO ACIDS ON SOLID SUPPORTS PHARMACORE, INC. (US) 2002-06-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167131-A1 Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade TFPI, SERPINC1, F11 USP2 1689/4885SMN1; SMN2 2662/4885GHSR 3781/4885
US-12527779-B2 Prostaglandin E2 (PGE2) EP4 receptor antagonists PTGER1, PTGER4, PTGER3 USP2 3878/4885SMN1; SMN2 3442/4885GHSR 939/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 USP2 4448/4885SMN1; SMN2 1555/4885GHSR 812/4885
US-20250223291-A1 IMIDAZOTRIAZINES AND IMIDAZOPYRIMIDINES AS KINASE INHIBITORS ERBB2, MERTK, ABL1 USP2 2420/4885SMN1; SMN2 3371/4885GHSR 1927/4885
US-20050075356-A1 Dihydroxypyrimidine carboxamide inhibitors of hiv integrase DUT, DPYD, TYMP USP2 3193/4885SMN1; SMN2 4143/4885GHSR 4716/4885
US-20260028341-A1 IMIDAZOTRIAZINE DERIVATIVES AS IL-17 MODULATORS IL17A, IL6ST, IL6 USP2 4323/4885SMN1; SMN2 3787/4885GHSR 1007/4885
US-12552804-B2 Tricyclic heterocycles as FGFR inhibitors FGFR3, FGFR1, FGFR2 USP2 4721/4885SMN1; SMN2 3900/4885GHSR 350/4885
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP3, DPP7, DPP9 USP2 2150/4885SMN1; SMN2 1910/4885GHSR 76/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.