Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 9/20 | 0.91 |
| ▸ | CA1 known ✓ | P00915 | 9/20 | 0.91 |
| ▸ | CA2 known ✓ | P00918 | 9/20 | 0.91 |
| ▸ | CA9 | Q16790 | 9/20 | 0.91 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11608338 | 1.00 | CA12 (0.91) | CA12CA1CA2CA9NAAA | |
| SCHEMBL27880322 | 1.00 | CA12 (0.91) | CA12CA1CA2CA9NAAA | |
| SCHEMBL15158111 | 1.00 | CA12 (0.91) | CA12CA1CA2CA9NAAA | |
| SCHEMBL9719002 | 1.00 | CA12 (0.91) | CA12CA1CA2CA9NAAA | |
| SCHEMBL15463371 | 1.00 | CA12 (0.91) | CA12CA1CA2CA9NAAA | |
| SCHEMBL11005394 | 1.00 | CA12 (0.91) | CA12CA1CA2CA9NAAA | |
| SCHEMBL10976175 | 1.00 | CA12 (0.91) | CA12CA1CA2CA9NAAA | |
| SCHEMBL2723880 | 0.98 | CA12 (0.95) | CA12CA1CA2CA9NAAA | |
| Potassium Ion SCHEMBL8509938 | 0.95 | CA12 (1.00) | CA12CA1CA2CA9NAAA | |
| SCHEMBL15570905 | 0.95 | CA12 (0.91) | CA12CA1CA2CA9NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117160683-A | Collophanite direct flotation collector and preparation method thereof | 湖北省长江资源循环利用及装备创新中心有限公司 | 2023-12-05 | — | — | CN | claimed |
| CN-117160683-A | Collophanite direct flotation collector and preparation method thereof | 湖北省长江资源循环利用及装备创新中心有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-115719800-A | Original state ultrathin carbon-coated metal sulfide nano-dot material and preparation and application thereof | 中南大学 | 2023-02-28 | — | — | CN | disclosed |